The migrasome is a novel organelle discovered in 2014. It is a vesicular structure with a diameter of approximately 0.5-3 micrometers, gradually growing at the cross nodes or tips of the retraction fibers at the rear end of cell migration. The migrasome contains a large number of biomacromolecules such as proteins, nucleic acids, and varying numbers of small vesicles, each with a diameter of around 50 nanometers. Migrasomes are widely present in various cells, tissues, and organs. They play a crucial role in cell-cell communication, the delivery of material and information, and the construction of the cellular micro-environment. They are also involved in important physiological and pathological processes such as mitochondrial quality control, embryonic development, angiogenesis, and likely play roles in various disease settings such as cancer metastasis.
In recent years, an increasing number of researchers worldwide have joined the field, leading to many significant and novel research advancements. Migrasome biology is emerging as a nascent field. To further promote the healthy development of migrasome biology, the '1st International Migrasome Conference' will gather scientists and research teams from around the world who are engaged in migrasome research and have an interest in migrasomes.
The conference aims to introduce the latest research advancements, facilitate in-depth discussions, seek collaboration opportunities,and create a favorable development environment for migrasome research. The SMART first International Symposium on Migrasome to be held from November 14 to November 15.
The tentative sessions include:
Biogenesis of migrasome
Biological function of migrasome
Clinical application of migrasome
Technology of migrasome research