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第六届疫苗创新国际论坛是一个致力于推进疫苗科学和全球健康的顶级国际盛会。在之前论坛的巨大成功基础上,今年的会议旨在进一步巩固其作为专家、研究人员、政策制定者和行业领导者的重要交流平台的声誉;从全球视角,推动免疫、疫苗、全球健康等领域的产、学、研、政府及非政府组织间的国际创新及合作。

 120+ 演讲嘉宾

1000+国际参会代表

30+国家和地区

60+参展单位



科学顾问委员会

Vaccine Innovation Forum World 2025-中文站点

Vaccine Innovation Forum World 2025-中文站点

Vaccine Innovation Forum World 2025-中文站点

Vaccine Innovation Forum World 2025-中文站点

Vaccine Innovation Forum World 2025-中文站点

Vaccine Innovation Forum World 2025-中文站点

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往届照片


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关键议题

Novel Vaccine Innovation:

Infectious diseases

RNA Technology

Bacterial vaccines

Veterinary Vaccines

Cancer Vaccines & Immunotherapies

Bioprocessing & Manufacturing

Clinical Trial/Vaccine Safety

Market Access/Regulatory/International Partnership

Adjuvant, Formulation, and Delivery Technologies

Global Health and Disease Prevention


数据

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会议评价

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学术壁报展示

 

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1对1约见系统

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联系我们

Sam Li 13482341046

sam.li@chstone-events.com

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赞助与合作

申请成为展商或赞助商

联系:Sam Li

sam.li@chstone-events.com

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1对1约见

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欢迎参加 VIF World 2025 的独家一对一合作会议。在这里,疫苗和生物制药领域的领军人物和创新者将进行深入交流。这是一个难得的机会,让参会者寻找潜在的合作伙伴,并探索潜在的合作机会。不要错过与行业专家建立联系的良机,提升您对未来疫苗开发的理解。在线系统将在活动日期前一个月开放,敬请关注!


活动日程
2025-03-20
2025-03-21
2025-03-22
2025-03-20
09:00 -12:00
Main Conference
2025-03-20
08:53-08:55
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
杜笑寒
赛诺菲疫苗全球对外研发部资深总监
2025-03-20
08:55-09:00
Opening Remark
嘉宾
Vaccine Innovation Forum World 2025-中文站点
王宾
复旦大学特聘教授;艾棣维欣创始人
2025-03-20
09:00-09:45
Plenary Panel: Revolutionizing Global Health: The Future of Vaccine Technology and Innovation

Moderator: Sean Du

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Adrian V. S. Hill
Director, The Jenner Institute, Professor, University of Oxford , UK
Vaccine Innovation Forum World 2025-中文站点
高福
中科院院士、教授
Vaccine Innovation Forum World 2025-中文站点
Dan Barouch
Professor, Harvard Medical School
Vaccine Innovation Forum World 2025-中文站点
Francesco Berlanda Scorza
VP R&D, Global Health R&D Vaccines Head and GVGH Institute, GSK, Belgium
Vaccine Innovation Forum World 2025-中文站点
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany
Vaccine Innovation Forum World 2025-中文站点
杜笑寒
赛诺菲疫苗全球对外研发部资深总监
2025-03-20
09:45-10:30
Plenary Panel: Global Vaccine Equity: Overcoming Challenges in Distribution and Access

Moderator: Raman Rao

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Rajinder Suri
CEO, DCVMN International, India
Vaccine Innovation Forum World 2025-中文站点
Raman Rao
CEO, Hilleman Laboratories
Vaccine Innovation Forum World 2025-中文站点
Hun Kim
President of Global Business, SK Bioscience, South Korea
Vaccine Innovation Forum World 2025-中文站点
王靖
执行董事&首席商务官,康希诺生物,中国
Vaccine Innovation Forum World 2025-中文站点
梁晓峰
中国预防医学会副会长,暨南大学教授
2025-03-20
10:30-11:00
茶歇
2025-03-20
11:00-11:25
Keynote: Innovative Vaccine Platforms: Accelerating Global Health R&D
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Francesco Berlanda Scorza
VP R&D, Global Health R&D Vaccines Head and GVGH Institute, GSK, Belgium
2025-03-20
11:25-11:50
Correlates of Protection for Respiratory Virus Vaccines
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Dan Barouch
Professor, Harvard Medical School
2025-03-20
11:50-12:15
AI-Guided and Structure-Based Vaccine Design
嘉宾
Vaccine Innovation Forum World 2025-中文站点
高福
中科院院士、教授
2025-03-20
12:15-13:30
午餐
2025-03-20
13:30 -17:30
Track A: Respiratory diseases/Flu/Covid
2025-03-20
13:28-13:30
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
舒跃龙
中国医学科学院病原生物学研究所所长、教授
2025-03-20
13:30-13:55
Pan-sarbeCoV vaccine: a dream or reality?

The current COVID-19 failed in protection of infection by SARS-CoV-2 variants. It is clear that we need a much better vaccine(s) which has a broad-spectrum protection against the current circulating variants as well as further related viruses.  Learning from the broad immunity observed in SARS survivors who subsequently received COVID-19 vaccine and/or got infected with SARS-CoV-2, we have adopted a cross-clade boosting strategy to develop pan-sarbeCoV vaccines which have demonstrated broad neutralization ability against all current variants as well as sarbeCoVs in clade-1a and clade-2 and -3.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
王林发
杜克-新加坡国立大学医学院教授
2025-03-20
13:55-14:20
mRNA Vaccines in Low- and Middle-Income Countries: Bridging the Gap
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Kiat Ruxrungtham
Director of Chula Vaccine Research Center, Chulalongkorn University
2025-03-20
14:20-14:45
Impact of glycosylation on a broad-spectrum vaccine against influenza

Influenza epidemics and pandemics caused by newly emerging virus strains highlight an urgent need to develop a universal vaccine against viruses. Previously, a monoglycosylated X-181mg vaccine demonstrated that the HA possessing a single N-acetylglucosamine at each N-glycosylation site is superior to confer broader protection in mice than conventional vaccines. However, the greatest challenge in conducting clinical trials is the need to develop robust manufacturing processes capable of producing vaccines at the pilot scale with the desired stability, potency, and efficacy. Whether the monoglycosylated virus vaccine platform can be applied to the new vaccine strain in a timely manner and whether the mass-produced vaccine has the proper immunogenicity to induce cross-protective immunity remains unclear. Here, we show that a pilot-scale manufacturing process produced a monoglycosylated A/Brisbane/02/2018(H1N1) virus vaccine (IVR-190mg) with a single glycan at each glycosylation site of HA and NA. Compared with the fully glycosylated virus vaccine (IVR-190fg), the IVR- 190mg provided broader cross-protection in mice against a wide range of H1N1 variants. The enhanced antibody responses induced by IVR-190mg immunization include higher hemagglutination-inhibition titers, higher neutralization activity, more anti-HA head domain, more anti-HA stem antibodies, higher neuraminidase activity inhibition titers, and notably, higher antibody-dependent cellular cytotoxicity. Additionally, the IVR-190mg also induced a more balanced Th1/Th2 response and elicited broader splenic CD4+ and CD8+ T-cell responses than IVR-190fg. This study demonstrated that IVR-190mg produced using a pilot-scale manufacturing process elicits comprehensive cross-strain immune responses that have great potential to substantially mitigate the need for yearly reformulation of strain-specific inactivated vaccines.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
陳俊叡
润惠生技运营长,中国
2025-03-20
14:45-15:00
A New Strategy for Vaccine Immune Evaluation System
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Chongyang Liang
Prof., Jilin University;Scientific Advisor, ProMab Forethought;
2025-03-20
15:00-15:30
General Considerations for the Non-clinical Safety Evaluation of Preventive mRNA Vaccines
嘉宾
Vaccine Innovation Forum World 2025-中文站点
胡颖
毒理二部主任, 昭衍(苏州)新药研究中心有限公司
2025-03-20
15:30-16:00
茶歇
2025-03-20
16:00-16:25
Decoding Antibody Response to MERS-CoV in Wild Dromedary Camels
嘉宾
Vaccine Innovation Forum World 2025-中文站点
张林琦
清华大学教授
2025-03-20
16:25-16:40
Vaccine Clinical Trials: Practical Insights to Avoid Pitfalls
嘉宾
Vaccine Innovation Forum World 2025-中文站点
莫兆军
斯丹姆医药疫苗临床业务/上海斯丹姆总经理
2025-03-20
16:45-17:10
Clinical development for RSV vaccine in China
嘉宾
Vaccine Innovation Forum World 2025-中文站点
谭巍
三叶草生物高级副总裁,中国研发及外部合作负责人
2025-03-20
17:10-17:35
Pan-β-coronavirus vaccine development
嘉宾
Vaccine Innovation Forum World 2025-中文站点
姜世勃
复旦大学教授
2025-03-20
17:30-18:30
Poster Session
2025-03-20
18:30-20:00
Welcome Cocktail Party (Invited only)
2025-03-20
13:30 -17:30
Track B:Cancer Vaccine & Immunotherapy
2025-03-20
13:28-13:30
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
王宾
复旦大学特聘教授;艾棣维欣创始人
2025-03-20
13:30-13:55
Immunotherapy for Cancer
嘉宾
Vaccine Innovation Forum World 2025-中文站点
David Weiner
Executive Vice President, The Wistar Institute, USA
2025-03-20
13:55-14:20
Development of mRNA vaccines: from infectious diseases to oncology
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany
2025-03-20
14:20-14:45
Expanding the Frontier: mRNA Vaccines for Cancer and Autoimmune Diseases(TBD)
嘉宾
Vaccine Innovation Forum World 2025-中文站点
英博
创始人,董事长兼首席执行官,艾博生物
2025-03-20
14:45-15:00
SynNeogen: unleash the power of immune system
嘉宾
Vaccine Innovation Forum World 2025-中文站点
陆汉新
凯米生物研发副总裁
2025-03-20
15:00-15:25
Precision treatment of pancreatic cancer - personalized tumor treatment vaccine
嘉宾
Vaccine Innovation Forum World 2025-中文站点
胡兰靛
深圳安达生物CEO
2025-03-20
15:30-16:00
茶歇
2025-03-20
16:00-16:25
Induction of tertiary lymphatic structures (TLS) by a novel immunotherapeutic strategy against solid tumors
嘉宾
Vaccine Innovation Forum World 2025-中文站点
王宾
复旦大学特聘教授;艾棣维欣创始人
2025-03-20
16:25-16:50
mRNA Vaccine Platform Technologies with Good Efficacy, Safety and Stability Validated in Several Clinical Trials

1. Clinical Data – Presenting groundbreaking progress in liver cancer treatment, including clinical trial data from the WGc-0201 project, demonstrating its safety, efficacy, and immunogenicity.

2. Platform Technology Highlights – Showcasing WestGene’s proprietary delivery systems and mRNA sequence design, backed by independent intellectual property.

3. Breakthrough Potential – Highlighting the disruptive potential of mRNA technology in tumor immunotherapy.



嘉宾
Vaccine Innovation Forum World 2025-中文站点
宋相容
威斯津生物创始人总经理
2025-03-20
16:50-17:15
A therapeutic cancer vaccine platform enhancing cross-presentation and CD8+ CTL response through targeting dendritic cell cytosol
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Joon Haeng Rhee
Professor, Chonnam National University Medical School, South Korea
2025-03-20
13:30 -17:30
Track C: DCVMN Forum
2025-03-20
13:28-13:30
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Rajinder Suri
CEO, DCVMN International, India
Vaccine Innovation Forum World 2025-中文站点
王子龙
董事会高级顾问,沃森生物,中国
2025-03-20
13:30-13:55
Strengthening Vaccine Manufacturing Capacity in Developing Countries: The Role of DCVMN
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Rajinder Suri
CEO, DCVMN International, India
2025-03-20
13:55-14:20
Overview of HPV vaccine development and global vaccine introduction status
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Peter Dull
Deputy Director, Gates Foundation, USA
2025-03-20
14:20-14:45
China Vaccine Industry Overview
嘉宾
Vaccine Innovation Forum World 2025-中文站点
袁瑗
中国国家代表, PATH
2025-03-20
14:45-15:10
BioKangtai’s Strategy and Technology Transfer Practices in the Era of Global Vaccine Cooperation
嘉宾
Vaccine Innovation Forum World 2025-中文站点
张骞
康泰生物国际业务部总经理
2025-03-20
15:10-15:45
茶歇
2025-03-20
15:45-16:10
Development of the vaccine production facility and tech transfer in Latin America
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Adel Sattarova
Head of Project Management Department, FSUE SPbSRIVS FMBA of Russia
2025-03-20
16:10-16:35
Future prospects for vaccine R&d and manufacturing
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Hun Kim
President of Global Business, SK Bioscience, South Korea
2025-03-20
16:35-17:00
Innovative products for low resource settings
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Melanie Saville
CSO, PATH, USA
2025-03-20
13:30 -17:30
Track D: Mucosal Immunizatioin Forum
2025-03-20
13:28-13:30
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Ling Chen
Professor, Guangzhou Laboratory
Vaccine Innovation Forum World 2025-中文站点
Diana Boraschi
Distinguished Professor, Shenzhen Institute of Advanced Technology, China
2025-03-20
13:30-13:55
Systemic and mucosal immunity: separate roles and cooperation
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Rita Carsetti
国际免疫学会联盟副主席;意大利Bambino Gesù儿童医院教授
2025-03-20
13:55-14:20
Inhaled Adenovirus (Human type 5) Vectored Tuberculosis Vaccine

Tuberculosis (TB) remains one of the world’s leading causes of death from a single infectious agent, Mycobacterium tuberculosis (Mtb). Despite the wide administration of the Bacille Calmette Guerin (BCG) vaccine, which offers variable, age-dependent protection, the need for a new vaccine effective across all age groups and for population with latent tuberculosis infection (LTBI) is essential for achieving the WHO's End TB Strategy. Recent data suggested that future vaccine designs should prioritize on eliciting lung-localized adaptive immune responses. Promising clinical results from CanSinoBIO’s first-generation TB vaccine, Ad5-Ag85A, highlight the crucial role of mucosal immunity in defending against TB. Currently, CanSinoBIO is in a quick process of the development of the new generation TB vaccine, ADTB, designed as an inhalation booster for individuals immunized with BCG, aiming to prevent new TB infections and the reactivation of LTBI. Utilizing a well-established adenovirus vector, ADTB carries three fused antigens and will be delivered via inhalation, a route successfully employed for CanSinoBIO’s Convidecia AirTM, the world's first inhaled COVID-19 vaccine. Extensive data from clinical trials and post-commercialization studies have proved the safety and efficacy of inhaled Ad5-vectored COVID-19 vaccines. The immunogenicity study of new generation TB vaccine in animal model demonstrated that the lower dose of ADTB can stimulated more robust cellular immune responses locally in the lungs, as well as systemically in the blood and spleen. The protection efficacy results indicated that ADTB effectively inhibits Mtb growth in the lungs and prevents lung damage. Overall, the promising preclinical data encourage further clinical trials of the ADTB vaccine.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
徐方
高级科学家,康希诺生物,中国
2025-03-20
14:20-14:45
The nose knows why and how

The nose is far more than just a passive tube to get air to the lungs. It serves as a sophisticated and dynamic immune barrier. In this regard, the nose is a critical component of the body's immune defense system, equipped with multiple mechanisms to detect, regulate, and respond to potential threats, thereby playing a vital role in maintaining respiratory health. The nose knows why and how.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Huimin Yan
Professor, Fudan University
2025-03-20
14:45-15:10
A sequential Intranasal Protein Vaccine Triggers Class Switching from Intramuscularly Primed IgG to Mucosal IgA against SARS-CoV-2

Current intramuscular (IM) COVID-19 vaccines inadequately protect the upper respiratory mucosa. In response, we have developed a nonadjuvanted, interferon-armed SARS-CoV-2 fusion protein vaccine with IM priming and intranasal (IN) boost sequential immunization. Our study shows that this sequential vaccination strategy of the IM+IN significantly enhances both upper respiratory and systemic antiviral immunity in a mouse model, marked by rapid enhancement in systemic and mucosal T and B cell responses, particularly the mucosal IgA antibody response. The IN boost triggers a swift secondary immune response, rapidly inducing antigen-specific IgA+ B cells. Further BCR-seq analysis indicates that these IgA+ B cells primarily arise through direct class switching from pre-existing IgG+ B cells in draining lymph nodes. Notably, our clinical studies reveal that the IN boost after IM vaccination elicits a robust IgA antibody response in humans. Thus, our cytokine-armed protein vaccine presents a promising strategy for inducing rapid and potent mucosal protection against respiratory viral infections.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
彭华
研究员,广州实验室,中国
2025-03-20
15:10-15:40
茶歇
2025-03-20
15:40-16:05
From Design to lmmunogenicity: An Intranasal Respiratory Syncytial Virus Vaccine Targeting Prefusion F Protein
嘉宾
Vaccine Innovation Forum World 2025-中文站点
魏霞蔚
研究员,四川大学华西医院
2025-03-20
16:05-16:30
Swab and Spray: Precision Vaccination with Nasal Vaccines

Respiratory infections begin with invading through the upper respiratory tract. Lessons learned from the SARS-CoV-2 pandemic have shown that higher levels of nasal spike-specific secretory IgA (sIgA) correlate with a lower risk of reinfection. Previously, we found that nasal sIgA is 100 times more potent than serum IgG in neutralizing Omicron subvariants. As mucosal sIgA levels decline over time, then the risk of reinfection increases. Can a nasal vaccine be designed to induce mucosal sIgA? Can the risk of infection be predicted by assessing the level of sIgA in the nasal mucosa? We propose a precision vaccination strategy: a simple self-test strip to monitor sIgA levels using a nasal swab; if the sIgA falls to a low level, a nasal spray of a vaccine can be given. This precision vaccination strategy will provide convenient and effective protection to people in need.



嘉宾
Vaccine Innovation Forum World 2025-中文站点
Ling Chen
Professor, Guangzhou Laboratory
2025-03-20
16:30-17:30
Open discussion
2025-03-21
09:00 -12:30
Track A: AMR&Biomanufacturing
2025-03-21
08:58-09:00
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Jeff Zhu
CEO, Ruizhou Bio
2025-03-21
09:00-09:25
The urgent need for new combination vaccines

The vaccination schedule has grown increasingly crowded, particularly for infants

Lack of space makes it challenging or impossible to introduce new life-saving vaccines

Combination vaccines may help by reducing crowding while reducing vaccine hesitancy

Challenges include formulation design, regulatory pathways, and how best to value combinations


嘉宾
Vaccine Innovation Forum World 2025-中文站点
Christopher Gill
Senior Program Officer, Vaccine Clinical Developmenta Gates Foundation, UK
2025-03-21
09:25-09:50
Rational design and generation of a noval recombinant Pseduomonas areaginosal subunit vaccine
嘉宾
Vaccine Innovation Forum World 2025-中文站点
顾江
教授,副主任,陆军军医大学
2025-03-21
09:50-10:20
Prophylactic Product Development and Manufacturing for Global Health Partners - A Systematic Approach
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Zhihui Qiu
Head of Alliance Management, WuXi Vaccines, China
2025-03-21
10:20-10:35
Harnessing mRNA Technology to Combat Antimicrobial Resistance: Pioneering Vaccines for Drug-Resistant Bacteria
嘉宾
Vaccine Innovation Forum World 2025-中文站点
费才溢
澄实生物创始人、副总裁
2025-03-21
10:35-11:00
茶歇
2025-03-21
11:00-11:25
Isolation of protective monoclonal antibodies and development of novel fusion protein vaccines against tuberculosis

Tuberculosis (TB) is the oldest and most deadly pandemic in history, still causing about 1.3 million deaths in 2022. BCG vaccination in humans results in the production of functional antibodies and long-lived memory B cell responses. We have showed that antibodies taken from protected healthcare workers (ie. individuals who were highly exposed to Mtb but remained uninfected) and transferred into mice could protect those mice against Mtb infection. It remains unknown which Mtb or BCG antigens induce protective antibody responses and what the mechanisms of such protective antibodies may be. In this study, two combinational antibody isolation methods were used to isolate the monoclonal antibodies against BCG/Mtb antigens. By the first method, the known protective antigens were used for mAbs isolation by single B cell isolation and Hybridima techniques, and the specific mAbs were isolated and the protective mAbs were identified by ex vivo and in vivo assay. By another method, the whole bacteria and the outer-membrane proteins of BCG were used, and then the B cells or the hybridoma technology was used to select the antibodies targeting the antigens. The protective functional activity of these mAbs were evaluated by using ex vivo and in vivo M.tb infection models, and the protective antigens were identified and used for the subunit vaccines development, which have shown protection in the mouse model. This research will promote a better understanding of host protective immune responses and the rational approach for the development of novel and effective TB vaccines.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
李浩
中国农业大学动物医学院副教授
2025-03-21
11:25-11:40
More than a theory - Successful vaccination by Micro Array Patches
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Markus Winterberg
Head, Analytical Development, Microbiology, Quality Control – MAP Program, LTS, Germany
2025-03-21
11:55-12:10
A High-Density Microarray Patch (HD-MAP) to Improve Effectiveness of Vaccines
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Thomas Lake
SVP Vaccine Alliances, Vaxxas, Autralia
2025-03-21
12:15-13:30
午餐
2025-03-21
09:00 -12:30
Track B:Emerging & Re-emerging Diseases
2025-03-21
08:58-09:00
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
成百麟
韩国疫苗创新技术联盟总干事
2025-03-21
09:00-09:25
Malaria Vaccines: from Licensure to Elimination

-       Overview of new high efficacy licensed R21/MM malaria vaccine

-       Next steps for Oxford – SIIPL multi-stage malaria vaccines

-       The road to elimination and eradication with new high-efficacy malaria vaccines


嘉宾
Vaccine Innovation Forum World 2025-中文站点
Adrian V. S. Hill
Director, The Jenner Institute, Professor, University of Oxford , UK
2025-03-21
09:25-09:50
Rational design of Zika vaccine to eliminate dengue enhancement
嘉宾
Vaccine Innovation Forum World 2025-中文站点
戴连攀
中科院微生物研究所研究员
2025-03-21
09:50-10:15
Innovative immunogen design for mpox virus vaccine development

The   worldwide outbreak of mpox virus (MPXV) in 2022 and the emergence and spread   of a new strain, clade Ib, in Africa in 2024 highlight the threat of a   sustained global epidemic of MPXV; however, the existing vaccines, attenuated virus   vaccine and replication-deficient virus vaccine, have raised concerns about   either their safety or efficacy. By using a structure-guided multi-antigen   fusion strategy, we design a ‘two-in-one’ immunogen, DAM, containing the   single-chain dimeric MPXV extracellular enveloped virus antigen A35   bivalently fused with the intracellular mature virus antigen M1. DAM   preserved the natural epitope configuration of both components and resulted   in stronger A35-specific and M1-specific antibody responses and more robust   neutralizing antibody titers than either co-immunization strategy or live   virus vaccination, collectively conferring effective in vivo protection from   MPXV challenge. Moreover, DAM showed comparable systemic immune responses and   in vivo protection with iteratively designed quadrivalent-chimeric immunogens,   demonstrating the superiority of the design. Finally, faster tissue virus   clearance was observed in the live virus vaccine-immunized group, accompanied   by severe non-infectious tissue damage, suggesting a redundant immune   response. We therefore propose a safer profile for protein vaccines than for   live virus vaccines, again due to precise and effective immunization. These   findings provide innovative insights and a promising vaccine candidate for   the development of alternative vaccines against MPXV and other   orthopoxviruses.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
王寒
北京大学副教授
2025-03-21
10:15-10:30
Harnessing Opportunities: Unlocking the Potential for Clinical Trials in Africa
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Christopher Obwanga
East Africa Regional Manager, P-95, Nigeria
2025-03-21
10:30-11:00
茶歇
2025-03-21
11:00-11:25
Efficacy safety and immunogenicity of hexavalent rotavirus vaccine in China
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Gelin Xu
Senior expert,Wuhan Institute of Biological Products ltd co.
2025-03-21
11:25-11:50
Assembly of Virus-like Particles Harnessed with RNA-based Chaperone

Assemblages   of key immunologic features of viruses as highly repetitive particulate   structures are essential for inducing potent and long-lasting antibody   responses. Capitalizing on a novel function of RNAs as chaperone (Chaperna),   here we provide a robust protein folding vehicle that could be implemented   for virus-like particle (VLP) or nanoparticle (NP) assemblies in bacterial   host. Here, tRNA functions as a ‘pace-maker’ for the assembly by controlling   the overall kinetic network of antigen folding pathway into immunologically   relevant conformation. Proof-of-concept was established for variety of NP   vaccines, including H5N1 influenza, RSV, Dengue fever, West Nile, Japanese   Encephalitis, VLP vaccines for Norovirus and subunit vaccine against   pertussis. The Chaperna platform enables bacterial production and delivery of   low-cost vaccines as a high-priority vaccine strategy against emerging and   re-emerging viral infections.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
成百麟
韩国疫苗创新技术联盟总干事
2025-03-21
11:50-12:15
A quadrivalent mRNA vaccine candidate elicited potent immune responses against monkeypox virus and protection in a rodent model

The global outbreak of the 2022 monkeypox virus (Mpox) infection of humans raised public health concerns about the threat of human-to-human transmission of zoonotic diseases and the recent escalating outbreak of the deadly clade 1b Mpox in Africa triggered the declaration of a global public health emergency. At present, there is an unmet need to contain the outbreak due to some serious adverse reaction of the existing vaccines, to be confirmed efficacy against Mpox in at-risk populations and constrained vaccine supply. Development of a safe, more effective and scalable vaccine against Mpox is imminent to address this continental and global health crisis as quickly and equitably as possible. We have developed a novel mRNA vaccine candidate expressing four vaccinia viral antigens A27, L1, A33, and B5 in tandem in one molecule and evaluated the vaccine immunogenicity in rodent models. Immunization of animals with the candidate mRNA vaccine induced a potent cellular immune response and long-lasting antigen-specific binding antibody and neutralizing antibody responses in rodents. Strikingly, the neutralizing antibody responses against vaccinia virus (VACV) and Mpox were significantly stronger than the existing live attenuated vaccine. The mRNA vaccine completely protected mice from VACV induced fatality and significantly reduced pulmonary viral load and histopathology induced by VACV challenge. From a manufacturing perspective, the novel design of the mRNA vaccine facilitated a simplified manufacturing process with reduced cost but increased product competitivity. The results hold promise for this mRNA vaccine candidate to be used for protection of human in a Mpox pandemic.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
熊野林
副总裁,易慧生物上海/中慧元通,江苏
2025-03-21
09:00 -12:30
Track C: Vaccine Design
2025-03-21
08:58-09:00
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
李少伟
厦门大学教授
2025-03-21
09:00-09:25
A path toward broadly and durably protective vaccines
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Yoshimasa Takahashi
Director,National Institute of Infectious Diseases, Japan
2025-03-21
09:25-09:50
Structure-Based Vaccine Design: Innovations in Stabilizing Antigens and Addressing Emerging Viral Threats
嘉宾
Vaccine Innovation Forum World 2025-中文站点
李少伟
厦门大学教授
2025-03-21
09:50-10:15
Proteolysis-Targeting Live Vaccine Technologies

The usefulness of live attenuated virus vaccines has   been limited by suboptimal immunogenicity, safety concerns or cumbersome   manufacturing processes and techniques. We developed proteolysis-targeting   (PROTAR) vaccine technologies by using the host cell’s ubiquitin–proteasome   system to manipulate stabilization and degradation of viral proteins of   influenza viruses. We engineered the genome of influenza viruses in stable   cell lines engineered for virus production to introduce proteasome-targeting   domain(s), generating fully infective PROTAR viruses that were live   attenuated by the host protein degradation machinery upon infection. In mouse   and ferret models, PROTAR viruses were highly attenuated and able to elicit   robust and broad humoral, mucosal and cellular immunity against homologous   and heterologous virus challenges. The PROTAR vaccine approaches may be   broadly applicable for generating live attenuated vaccines.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
司龙龙
教授,深圳先进科技研究院
2025-03-21
10:15-10:30
TBC
2025-03-21
10:30-11:00
茶歇
2025-03-21
11:00-11:25
AI-assisted vaccine and adjuvant design by immunoswithing technology
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Ken Ishii
Director, International Vaccine Design Center, Professor, University of Tokyo, Japan
2025-03-21
11:25-11:50
Characterization of structural biology and immunology of virus-like structure vaccine
嘉宾
Vaccine Innovation Forum World 2025-中文站点
李琦涵
教授,利彤-威瑞生物,中国
2025-03-21
12:15-13:30
午餐
2025-03-21
09:00 -12:30
Track D: RNA Tech
2025-03-21
08:58-09:00
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Heinrich Haas
CTO, NeoVAC, UK
2025-03-21
09:00-09:25
Lipid nanoparticles for mRNA vaccine delivery
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Norbert Pardi
Associate Professor, University of Pennsylvania, USA
2025-03-21
09:25-09:50
Advanced quality control strategies for mRNA vaccines

Lipid nanoparticles (LNPs) comprising mRNA are applicable as vaccines but also for a scope of therapeutic purposes. Despite of several initiatives to align on standard panels for quality assessment of such mRNA vaccines, discussions for identifying best and appropriate control strategies are still ongoing. So far, the focus has been mostly on the properties of the molecular properties of the individual components (like identity, content, integrity).

However important quality-related aspects of such mRNA vaccines derive from their colloidal nature. They are intrinsically polydisperse, multicomponent systems, formed by self-assembly between the respective moieties. Size dependent structural properties, drug loading and local chemical-physical coherencies inside the particles should be addressed.

In this presentation, biophysical approaches to get better insight into such chemical-physical properties with relevance for quality of the mRNA LNPs are presented.



嘉宾
Vaccine Innovation Forum World 2025-中文站点
Heinrich Haas
CTO, NeoVAC, UK
2025-03-21
09:50-10:05
Formulation research and development of mRNA therapeutics based on stability, safety and accessibility
嘉宾
Vaccine Innovation Forum World 2025-中文站点
李亚霏
研发总监,瑞吉生物,中国
2025-03-21
10:05-10:30
RNA platform implementation in Brasil: Seeding the innovation ecosystem in Latin America
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Patrícia Neves
Project Manager, mRNA center,Bio-Manguinhos/ Fiocruz, Brazil
2025-03-21
10:30-11:00
茶歇
2025-03-21
11:00-11:25
mRNA vaccines and global health: addressing global unmet needs in infectious diseases
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany
2025-03-21
11:25-11:40
Comprehensive LNP Characterization from Cargo to Target Modification by Nano-Flow Cytometry

Analyzing Lipid-based Nanoparticles (LNPs) as vectors presents various technical challenges stemming from their complex structure, small size, and encapsulation efficiency. Successfully evaluating the loading ratio and RNA distribution within these particles is crucial for identifying high-quality candidates and optimizing formulation strategies to minimize waste.

The NanoAnalyzer offers a comprehensive solution to overcome the hurdles inherent in LNP analysis. NanoFCM has demostrated the effectiveness of nFCM analysis in addressing the complicated challenges of LNP characterization, including efficacy of nanoparticle loading, mRNA quantification, and the surface density of various targeting modalities.



嘉宾
Vaccine Innovation Forum World 2025-中文站点
王娜
应用工程师,福流生物
2025-03-21
11:40-11:55
Process Development for Circular RNA: Advancing Manufacturing Strategies
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Kaiyao Wei
Process Scientist,源兴基因
2025-03-21
11:55-12:15
Engineering Internal Architecture of Lipid Nanoparticles to Promote Efficient mRNA Endosomal Release

Lipid nanoparticles (LNPs) are the cornerstone of non-viral mRNA delivery systems, yet their therapeutic potential remains constrained by inefficient endosomal escape, with cytoplasmic delivery rates as low as 2%. Traditional approaches to enhancing endosomal release have primarily focused on chemical modifications of ionizable lipids. Here, we introduce a novel strategy centered on engineering the internal architecture within core-shell LNPs to substantially improve mRNA delivery efficiency. By utilizing ionizable lipid-coated gold nanoparticles (AuNPs) as a demonstrative core, we systematically optimized the LNP nanostructure, achieving a twofold increase in endosomal escape efficiency and a 100-fold enhancement in mRNA diffusion within the cytoplasm compared to conventional LNPs. This structural optimization also promotes more uniform and stable nanoparticle

assembly. In vitro studies demonstrated higher mRNA expression and transfection efficiency in HeLa and 293 cells treated with engineered core-shell LNPs. In vivo evaluations revealed a nearly fivefold increase in mRNA expression in murine models, alongside enhanced immunogenicity in SARS-CoV-2 spike-mRNA vaccines and therapeutic efficacy in a triple-negative breast cancer model. Comprehensive biocompatibility and biosafety assessments confirmed the favorable safety profile of the engineered LNPs. This internal architecture optimization framework provides a scalable and adaptable pathway for advancing mRNA therapeutics and vaccines, addressing a key bottleneck in endosomal release and paving the way for broader biomedical applications.


嘉宾
Vaccine Innovation Forum World 2025-中文站点
曹宇虹
研究员,国家纳米科学中心,中国
2025-03-21
13:30 -17:30
Track B: Clinical Development & Partnership
2025-03-21
13:28-13:30
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
宇文镐
斯丹姆医药高级副总裁,全球首席商务官
2025-03-21
13:30-13:55
Clinical data of single dose vaccine development for Rabies
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Sandy Douglas
Associate Professor, Oxford University, UK
2025-03-21
13:55-14:20
Efficacy and safety of a herpes zoster vaccine in clinical trial in China
嘉宾
Vaccine Innovation Forum World 2025-中文站点
李靖欣
江苏省疾控中心疫苗评价所副所长
2025-03-21
14:20-14:35
Global Vaccine Registration Strategy and Key Considerations
嘉宾
Vaccine Innovation Forum World 2025-中文站点
宇文镐
斯丹姆医药高级副总裁,全球首席商务官
2025-03-21
14:35-15:00
SYN023 an Monoclonal Cocktail for Rabies Prophylaxis
嘉宾
Vaccine Innovation Forum World 2025-中文站点
曹一孚
CEO,兴盟生物, 中国
2025-03-21
15:00-15:30
茶歇
2025-03-21
15:30-15:45
Vaccine clinical development strategy in emerging market(s) and Commercial potentials
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Adham Rezk
CEO, Rezk Ventures Singapore
2025-03-21
15:45-16:10
Enhancing Vaccine Equity through Global Partnerships and Local Manufacturing: Practices of Chinese Vaccine Manufacturers
嘉宾
Vaccine Innovation Forum World 2025-中文站点
李萌
中国生物国际合作部主任
2025-03-21
16:10-16:35
The RIGHT Foundation: Mobilizing Partnerships for Equitable Vaccine Access
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Hani Kim
Executive Director, The RIGHT Foundation, South Korea
2025-03-21
16:35-17:00
Chasing the miracles of science through strengthening external partnerships and development of ecosystems
嘉宾
Vaccine Innovation Forum World 2025-中文站点
杜笑寒
赛诺菲疫苗全球对外研发部资深总监
2025-03-21
13:30 -17:30
Track A: Adjuvant&Formulation
2025-03-21
13:28-13:30
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Joon Haeng Rhee
Professor, Chonnam National University Medical School, South Korea
2025-03-21
13:30-13:55
Enhancing Mucosal Immunity with RAR Agonists as Potent Vaccine Adjuvants
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Haibo Li
Professor, Army Medical University, China
2025-03-21
13:55-14:20
Empowering the Immunity: CpG adjuvants for vaccine development and cancer therapy

This talk will discuss the TLR9 pathway and novel CpG candidates that ParrBio has developed to unleash the potential of innate immune system to fight infectious diseases and cancer. We have shown that the novel type of CpGs can stimulate both humoral and cellular immunity and possess distinct characteristics comparing with the CpGs on the market. These novel types of CpGs have shown superiority when used as vaccine adjuvants and demonstrated potent anti-tumor activity in both animal models and in cancer patients. ParrBio is actively seeking global partners to advance its CpG compounds in vaccine development and cancer therapeutic drug application.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
王中辛
全球研发总裁,CSO,华普生物,中国
2025-03-21
14:20-14:50
Next Generation of Highly Effective Adjuvant Systems: Safe & Efficacious Vaccines Made Possible Through Partnerships, with Inimmune and SPI Pharma

Vaccines have a long history as one of the most effective methods for the prevention of infectious diseases, but a lack of approved vaccine adjuvants hinders the development of efficacious subunit vaccines. The impact of the vaccine adjuvant AS01 on the efficacy (97%) of the Shingrix vaccine is an excellent example of what can be achieved with the optimal combination of recombinant antigen and adjuvant system.   While a vaccine must be efficacious, an ideal vaccine should also be relatively easy to manufacture and stable within the existing supply chain in order to improve availability to both the developing and developed world.   Our team has developed several 3rd generation pattern recognition receptor agonists capable of being formulated with a wide variety of vaccine delivery systems (emulsions, liposomes, inorganic nanoparticles, etc.) providing a deep toolbox to enable the optimal pairing of adjuvant and antigen. In the work presented here, we evaluated recombinant A/Victoria/2009 monovalent detergent split influenza antigen in combination with our novel toll-like receptor agonist INI-2002 in combination with QS21 saponin in our AS01-like formulation called T4Q, administered intramuscularly. T4Q induces Th1-biased antigen-specific antibody and T cell responses similar to commercial AS01. Additionally, T4Q adjuvanted vaccination provides protection from heavily drifted influenza challenge that is 100% lethal after vaccination with antigen only. In our novel model for measuring injection site pain, T4Q does not demonstrate increased injection site pain compared to AS01. Having validated this injection site pain model will enable us to evaluate novel formulations in an effort to reduce injection site pain.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Juhienah Khalaf
Director of Chemistry, Inimmune Corp
2025-03-21
14:50-15:05
Industrial synthesis and application of saponin adjuvant QS-21-Api and its analogues
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Marcus Xiao
资深科学家,百达信生物
2025-03-21
15:05-15:35
茶歇
2025-03-21
15:35-16:00
Harnessing the power of TLR agonists as vaccine adjuvants

Until recently, development of new human adjuvants was held back by poor understanding of their mechanisms of action and associated safety concerns. Major investment has led to renewed activity in the adjuvant field, resulting in multiple new adjuvant discoveries. Vaxine has successfully developed an extensive range of new vaccine adjuvants including polysaccharides (delta inulin), various small molecule and oligonucleotide agonists of toll-like receptor (TLR)-2, 4, 7, 9 and NOD2, many identified and optimised using our AI-based in silico high throughput drug screening approach - our experience in use of AI for immunomics research dating back over 25 years when Professor Petrovsky was a founder of the field of Immuno-informatics.  These adjuvants alone and in combination can be used to tailor the immune response in any direction to get the desired outcome. However, adjuvants are just one piece of a successful vaccine, the other two pieces being the antigen platform and the delivery system. Vaxine has invested in optimizing each of these elements. It is utilising high yielding low-cost insect cell and C1 fungal protein expression platforms to produce its protein antigens, combining these with its proprietary adjuvants and then utilizing novel delivery systems including needle-free jet injectors, microneedle transdermal patches, aeosol lung delivery and intra-oral mucosal administration to ensure these are delivered to the right compartments to deliver a protective vaccine response. On top of this it is using AI to help speed the discovery and design of new antigens and adjuvant to feed this pipeline. This demonstrates major benefits in respect of enhanced protection when co-formulated with respiratory vaccines in animal models of influenza, SARS-CoV and tuberculosis, amongst many others. These adjuvants also have major effects on cellular and in particular, CD8 T cell immunity, with important implications for use in viral but also in cancer vaccines where induction of cytotoxic T cells is paramount. Thus the robust protection against respiratory pathogens afforded by these adjuvants when formulated with appropriate antigens can be ascribed to their ability to broadly enhance all arms of the adaptive immune response, resulting in generation of high avidity antibody and memory B cells as well as memory and effector CD4 and CD8 T cells.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Nikolai Petrovsky
Founder, Vaxine, Australia
2025-03-21
16:00-16:25
Nanoemulsion Adjuvants

The recombinant protein/polypeptide vaccine has become a new generation of vaccine technology, which will be widely used in the prevention and treatment of infectious diseases and tumors. However, the recombinant proteins/peptides need to be matched with appropriate adjuvants to become a valuable vaccine with especially cellular immunity. Adjuvants are a class of non-specific immune enhancers that can enhance the immunogenicity of antigens and change the type of immune response. The most widely used Alum adjuvants have good efficacy in increasing antibody immunity but are less effective in novel vaccines that require cellular immunity, such as tumor vaccines. In recent years, several novel innate immune agonists have been used in clinical trials for preventive and therapeutic vaccines. For example, the AS01 adjuvant developed by GSK, which combines two classes of agonists -MPLA and QS21- lipid nanoparticles, is successfully applied to the herpes zoster vaccine in 2018. Therefore, new adjuvants have become the core technology of the development pipeline of vaccine companies. Here, I will present our effort to develop new adjuvant formulation as nanoemulsion. We have obtained new nanoparticulate adjuvants without GS21 by using efficient agonists and formulation technique. The performance adjuvanted with antigens of VZV, Flu, RSV shows excellent antibody and cellular immunity with good safety. 

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Yongming Chen
Professor, Sun Yat-sen University
2025-03-21
16:25-16:50
Engineered design of aluminum-based combination adjuvants

Abstract: The development of high-purity antigens highlights the urgent need for novel adjuvants capable of triggering robust immune responses. Aluminum salts (Alum) are often employed as adjuvants but yield limited cellular immune responses. To address this limitation, Toll-like receptor (TLR) agonists have been utilized in combination with Alum. However, the current use of Alum and TLR agonists remains restricted to linear mixtures, and the interaction mechanism between TLR agonists and Alum is not well understood. In our study, we formulated combination adjuvants using aluminum oxyhydroxide nanorods (AlOOH NRs) and TLR agonists, such as CpG and Poly(I:C). The engineered combination adjuvants induce enhanced humoral and cellular immune responses in several antigen models, including HBsAg virus-like particles (VLPs), human papillomavirus (HPV) VLPs, and varicella-zoster virus (VZV) glycoprotein E (gE). Further mechanistic studies show that the formulation of combination adjuvants, such as the conjugation method, the orientation of the CpG molecule, and the molecular weight (MW) of Poly(I:C), determines the physicochemical properties and adjuvanticity of these combination adjuvants. Our study offers insights into adjuvant design to meet the formulation requirements for both prophylactic and therapeutic vaccines.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Bingbing Sun
Professor, Dalian University of Technology, China
2025-03-21
13:30 -17:30
Track C: Vaccine Tech Innovation
2025-03-21
13:28-13:30
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
SeyedReza Banihashemi
Director of R&D, Razi Vaccine & Serum Research Institute
2025-03-21
13:30-13:55
Innovative Delivery Methods for Next-Generation Vaccines: Nasal, Inhalable, and Beyond

The development of next-generation vaccines has opened new frontiers in immunization strategies, particularly through innovative delivery methods such as nasal sprays and inhalable formulations. These novel approaches offer significant advantages over traditional injection-based vaccines, including improved patient compliance, enhanced immune responses, and the potential for rapid mass immunization during pandemics. Nanotechnology plays a crucial role in these advancements by enabling the creation of nanoparticle-based vaccines. These nanoparticles can serve as carriers for antigens, enhancing the delivery and stability of vaccines. They can also act as adjuvants, boosting the immune response by targeting antigen-presenting cells more effectively12. This presentation will explore the latest advancements in vaccine delivery technologies, focusing on the mechanisms, benefits, and challenges associated with nasal and inhalable vaccines, as well as the integration of nanotechnology. Additionally, we will discuss the implications of these innovations for global health, particularly in low-resource settings, and the future directions for vaccine research and development.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
SeyedReza Banihashemi
Director of R&D, Razi Vaccine & Serum Research Institute
2025-03-21
13:55-14:20
The Molecular Clamp Platform: A broadly applicable solution to the manufacture of multivalent subunit vaccines for respiratory viruses

Respiratory syncytial virus (RSV), human metapneumovirus (hMPV) and parainfluenza virus 3 (PIV3) are medically important causes of respiratory tract infections. Combined these three viruses cause more severe disease and hospitalisations than influenza viruses. After more than 5 decades of unsuccessful research and development, vaccines have recently been approved for the prevention of lower respiratory tract disease caused by RSV, however vaccines for hMPV and PIV3 remain in early-stage development. The game changing development which lead to effective RSV vaccines has been discovery of methods to stabilize the RSV fusion glycoprotein (F) into the elusive prefusion conformation (preF).

The University of Queensland has developed a broadly applicable proprietary technology (molecular clamp), to facilitate preF stabilization not only for RSV but also hMPV and PIV3, and a diverse array of fusion glycoproteins from other viral families. In association with biotech spinout company, Vicebio Ltd, our team have identified lead candidate subunit vaccines for RSV, hMPV and PIV3, all of which have demonstrated, high yield, high stability and the ability to effectively elicit strong neutralizing immune response in animal models. The bivalent vaccine against RSV and hMPV (VXB-241) entered a phase I clinical trial in August 2024 and the trivalent formulation which also includes PIV3 (VXB-251) is completing pre-clinical development.

With three separate respiratory virus vaccines currently recommended for elderly populations (seasonal influenza, COVID-19 and RSV), the prospect of adding further vaccines for other high burden respiratory viruses such as hMPV or PIV3 into the schedule becomes problematic. Vicebio seeks to overcome this problem through the production of highly protective, multivalent vaccines in ready-to-use, liquid-stable formulations.



嘉宾
Vaccine Innovation Forum World 2025-中文站点
Keith Chappel
Group Lead, The University of Queensland, Australia
2025-03-21
14:20-14:55
An economical adjuvant without production limit to induce potent cell-mediated immunity in subunit vaccines

Compared with humoral immunity which blocks pathogen infection, cell-mediated immunity (CMI) clears infected cells to limit the replication and spread of pathogens. This increases vaccine efficacy against highly contagious (e.g., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)) or latent (e.g., herpesvirus) pathogens. Although FDA-approved AS01B, AS01E and matrix-M adjuvants can induce potent CMI in subunit vaccines, they rely on QS21, a polysaccharide extracted from the bark of Quillaja saponaria. Because massive synthesis of QS21 is infeasible and Q. saponaria occurs only in South America, the supply of these CMI-inducing adjuvants is limited (e.g., approximately 20 million doses annually for AS01B), resulting in higher prices for the corresponding vaccines (approximately 150-200 USD per dose of ShingrixTM compared with other vaccines normally sold at 10-40 USD per dose).

The FDA has recently approved ionizable lipid nanoparticles (LNPs) for COVID-19 mRNA vaccines as carriers and oligodeoxynucleotides containing CpG motifs (CpG ODNs) for hepatitis B subunit vaccine as immunostimulators, both could be synthesized economically. We developed a novel LNP-CpG ODN adjuvant and tested its potency in different subunit vaccines. In varicella-zoster virus (VZV) vaccines, which use glycoprotein E as an antigen, this vaccine induced levels of CMI, which plays a decisive role in the efficacy of zoster vaccines, comparable to those of ShingrixTM in a VZV-primed mouse model that was adopted for preclinical studies of ShingrixTM and in non-human primates. In addition to potent humoral responses (approximately 10 times greater than those induced by alum adjuvants after 2 injections), Th1-oriented CMI was induced in respiratory syncytial virus (RSV) vaccines via the use of stabilized fusion glycoprotein (F) as an antigen, which may be helpful for lowering the risk of antibody-dependent enhancement of immunopathology. For rabies virus (RABV) vaccines, the surface glycoprotein (RABV-G) was used as an antigen, and IgG antibodies were induced within 7 days of primary vaccination (compared with 14 days with alum as an adjuvant). Prompt-induced humoral immunity and potent CMI that are helpful for eradicating infected viruses may work synergistically for increasing RABV vaccine efficacy.

In conclusion, LNP-CpG ODN adjuvants are helpful for inducing prompt, potent humoral immunity and potent CMI for subunit vaccines


嘉宾
Vaccine Innovation Forum World 2025-中文站点
刘存宝
研究员,中国医学科学院医学生物学研究所,中国
2025-03-21
14:45-15:10
Amezosvatein Phase 2 trial results
嘉宾
Vaccine Innovation Forum World 2025-中文站点
George Simeon
CEO, Curevo Vaccine
2025-03-21
15:10-15:35
茶歇
2025-03-21
15:35-16:00
Innovating Plant-Based Vaccines: A New Frontier in Global Health

As the global demand for rapid, scalable, and cost-effective vaccine production grows, Baiya Phytopharm has emerged as a leader in plant-based vaccine technologies. Our novel vaccine platform harnesses the power of plants to produce vaccines faster and more sustainably than traditional methods. This presentation will showcase the science behind Baiya's platform, including its speed, scalability, and potential to address pandemics and rare diseases. We will also discuss our latest achievements, such as the development of COVID-19 vaccine candidates, and explore the future of plant-based biologics in global healthcare.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Suthira Taychakhoonavudh
CEO, Baiya Phytopharm, Thailand
2025-03-21
16:00-16:25
Revolutionizing Pneumococcal Vaccination: Advancing Towards a Universal Pneumococcal Vaccine Solution
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Tim Hirst
Chairman & CEO, GPN Vaccines
2025-03-21
16:25-16:50
Vaccine development based on DDS technology

I would like to discuss the vaccine technologies for nasal vaccine and mRNA vaccine.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Yasuo Yoshioka
Project Leader, BIKEN Center for Innovative Vaccine Research and Development, Japan
2025-03-21
13:30 -17:30
Track D: RNA Tech
2025-03-21
13:28-13:30
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Yuanqing Liu
CSO China, Immorna Biotherapeutics
2025-03-21
13:30-13:55
Mechanisms of vaccine reactogenicity

·         Overview of what is known about local and systemic symptoms post vaccination. Ex of adjuvanted and mRNA vaccines

·         Recent data at University of Geneva on mechanisms of reactogenicity of mRNA vaccines in humans and mouse models (collaboration with Moderna)

·         Key message: both vaccine-specific and host intrinsic factors contribute to reactogenicity

·         Perspectives for the development of improved vaccines


嘉宾
Vaccine Innovation Forum World 2025-中文站点
Arnaud Didierlaurent
Assistant Professor, Director of Center of Vaccinology,University of Geneva
2025-03-21
13:55-14:20
Revolutionizing Therapeutics with Next-Generation RNA Platforms: From Vaccines to Gene Therapy (TBD)
嘉宾
Vaccine Innovation Forum World 2025-中文站点
王子豪
嘉晨西海CEO
2025-03-21
14:20-14:45
Rational design of ionizable lipids for RNA delivery
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Xuexiang Han
Professor, SIBCB, China
2025-03-21
14:45-15:00
Making CircRNA a Reality in Preventive Vaccines
嘉宾
Vaccine Innovation Forum World 2025-中文站点
薛永博
高级研究科学家,毕昇生物
2025-03-21
15:00-15:15
Non-reactogenic LNPs addressing mRNA vaccination hesitancy

mRNA vaccines have revolutionized the response to infectious diseases, as demonstrated during the COVID-19 pandemic. However, these vaccines face significant challenges, including suboptimal delivery efficiency and high reactogenicity, leading to reduced vaccine acceptance. Our preliminary studies show that General Therapeutics' Next-generationiLDC LNPs can reduce pro-inflammatory cytokine levels by 50% and enhance mRNA expression up to 8-fold compared to traditional formulations, and more importantly being 70% less pain and tissue damage. mRNA vaccines formulated with our iLDCs will improve efficacy and reduce adverse reactions. Our LNP technology has the potential to significantly improve the safety and effectiveness of mRNA vaccines. By overcoming the limitations of current mRNA vaccines, this project aims to enhance vaccine safety and efficacy, addressing mRNA vaccination hesitancy, ultimately contributing to better global health outcomes.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Jiangsheng Xu
Founder& CSO, General Therapeutics, USA
2025-03-21
15:15-15:35
茶歇
2025-03-21
15:35-16:00
Pre-clinical development of a circular RNA vaccine against Nipah virus

Circular RNA (cRNA) vaccine is a promising alternative to the canonical linear RNA vaccine. Compared to linear RNA, cRNA has a longer half-life and could potentially be more thermostable and does not require extreme storage and transportation temperature. The goal of this study is to evaluate this novel cRNA platform through the development of a vaccine against Nipah virus. We assessed various cRNA encoding for the full-length (NiV-FL) or only the ectodomain of Nipah glycoprotein G in vivo and found that one of the cRNA-NiV-FL elicited better antibody and neutralizing antibody responses in a dose-dependent manner. Next, we evaluated the effect of various LNP for encapsulation of the cRNA in vivo and found that all of the novel LNP-encapsulated cRNA elicited higher antibody response in mice when compared to a clinically approved LNP. In conclusion, we have successfully performed preclinical proof of concept of a cRNA vaccine against Nipah. Future experiments involved further development of this cRNA vaccine into a viable and cost-efficient vaccine product.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Pei-Yin Lim
Senior Manager, Preclinical R&D, Hilleman Laboratories, Singapore
2025-03-21
16:00-16:25
Optimizations of VZV mRNA vaccine

We have successfully developed a sophisticated VZV mRNA vaccine by optimizing its antigen truncation, RNA sequence, and vaccination approach. Our study demonstrates that the RNA sequence optimized Full-length gE protein inoculated intradermally executes a better immunogenicity.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Wenshuo Zhou
Leading Scientist & CSO Academic Secretary, CNBG- Virogin Biotech, China
2025-03-21
16:25-16:50
Optimizing Tissue Distribution & Safety of LNP-Mediated Prophylactic Vaccines to Accelerate Prevention of Infection & Disease
嘉宾
Vaccine Innovation Forum World 2025-中文站点
李惠
深信生物研发总监,中国
2025-03-22
09:00 -12:30
Track A: Animal Vaccine
2025-03-22
08:58-09:00
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Frank Chang
CSO, Reber Genetics, China
2025-03-22
09:00-09:25
Advancing One Health: Integrating Veterinary and Human Vaccines to Tackle Global Health Challenges
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Alejandra Capozzo
Professor, Center Director, Universidad Abierta Interamericana (UAI), Argentina
2025-03-22
09:25-09:50
Trying to hit a moving target: New approaches to porcine reproductive and respiratory syndrome virus vaccine development

Porcine reproductive and respiratory syndrome viruses (PRRSV) cause significant economic losses in the global pig industry. Live attenuated PRRSV vaccines (MLV) are widely used but are weakly immunogenic and provide limited protection. There is therefore a pressing need to develop more efficacious next generation vaccines. I shall present three examples of novel approaches we have or are pursuing: (i) evaluation of the induction of broadly protective cellular immunity; (ii) augmenting protection by engineering MLV to express immune checkpoint inhibitors; and (iii) the application of structural vaccinology to develop a vaccine capable of inducing broadly neutralising antibodies.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Simon Graham
Professor, The Pirbright Institute, UK
2025-03-22
09:50-10:15
Strategies for prevention and control of animal diseases: progress and future development of virus-like particle vaccines against foot-and-mouth disease
嘉宾
Vaccine Innovation Forum World 2025-中文站点
董虎
副教授,兰州兽医研究所,中国
2025-03-22
10:15-10:35
Development and Application of innovative adjuvants in animal vaccines
嘉宾
Vaccine Innovation Forum World 2025-中文站点
冯华朋
副教授,浙江理工大学,中国
2025-03-22
10:35-11:00
茶歇
2025-03-22
11:00-11:25
African swine fever virus antigen discovery
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Christopher Netherton
Professor, The Pirbright Institute, UK
2025-03-22
11:25-11:50
Progress and prospect of animal vaccine research and development
嘉宾
Vaccine Innovation Forum World 2025-中文站点
李劼
金宇保灵生物研发总监
2025-03-22
11:45-12:05
Revolutionizing Animal Vaccine Development: The Role of mRNA and Exosome Platforms
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Frank Chang
CSO, Reber Genetics, China
2025-03-22
12:05-12:25
The development of PDCoV and PEDV mRNA vaccines
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Zhong Chen
Vice President, Suzhou HealiRNA Biotechnology
2025-03-22
09:00 -12:30
Track B: Immune Mechanisms & Vaccine Design
2025-03-22
08:58-09:00
Chair
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Aldo Tagliabue
Chief Scientist, Shenzhen Institute of Advanced Technology, China
2025-03-22
09:00-09:25
Innate Immunity and Vaccine Adjuvant Innovation: Leveraging the Body's First Line of Defense
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Diana Boraschi
Distinguished Professor, Shenzhen Institute of Advanced Technology, China
2025-03-22
09:25-10:10
Vaccine adjuvants, mRNA mode of action, innate/trained immunity for vaccines

-Adjuvants induce innate immune responses that correlate with adaptive responses

-There is increasing evidence that some of these innate responses are accompanied by chromatin changes in monocytes, giving rise to the phenomenon of trained immunity

-Deciphering the molecular pathways and signalling targets can inform rational design of novel adjuvants, including those that can be combined with mRNA/LNP formulations

-Connecting in-depth understanding of adjuvant immunity can inform design choices and research directions for mRNA 2.0


嘉宾
Vaccine Innovation Forum World 2025-中文站点
Robbert van der Most
Former VP, Translational Science, BioNTech/ CEO, VaxxCellence
2025-03-22
10:05-10:30
TBC
嘉宾
Vaccine Innovation Forum World 2025-中文站点
曹云龙
北京大学研究员
2025-03-22
10:30-11:00
茶歇
2025-03-22
10:30-10:55
Immunogenicity testing of pan-variant influenza and coronavirus vaccines using pseudotype platform technologies

1.     Background of pseudotype technologies

2.     Building pseudotype platforms

3.     Immunogenicity readouts for broadly-reactive vaccines

4.     Novel directions of pseudotype technology


嘉宾
Vaccine Innovation Forum World 2025-中文站点
Nigel Temperton
Professor, Director, Viral Pseudotype Unit, University of Kent, UK
2025-03-22
10:55-11:10
Bioassay for vaccine efficacy
嘉宾
Vaccine Innovation Forum World 2025-中文站点
Emanuele Montomoli
Co-founder& CSO, VisMederi, Italy
2025-03-22
11:40-12:05
Antigenic sin drives B cell evolution: lessons learned from the COVID-19 pandemic

The COVID-19 pandemic led to an unprecedented event, all people woridwide were exposed for the first time to the same virus, SARS.CoV.2 Wuhan, creating a globally shared original antigenic sin (OAS). However, during the course of the COVID-19 pandemic several varianis emerged exposing the human immune system to numerous antigenically distinct spike (S) proteins, the main target neutralizing antibodies. This unceasing interplay between SARS-CoV-2 variants and the human immune system has led to a  continuous maturation of the B cell compartment rising questions on how the SARS-CoV-2 Wuhan OAS memory B cell response evolvedcontroemerging variants. To shed light on the impact of SARS-CoV-2 0AS on B cellimmunity we longitudinaly analyzed at single celIevel spanel of almost 1,000 neutralizing human monoclonal antibodies (nAbs) isolated from COVID-19 vaccinees or people with hybrid immunity. Our analysis revealed that the Wuhan OAS,drove convergent maturation and expansion germlines(GHV3.53/3-66) which were restor to neutralize SARS-CoV-2 Omicron variants. In addition, we observed that after breakthrough infection with the antigenical distant Wuhan Omicron, people expanded new B cell germlines not derived by the Wuhan OAS to tackle SARS-CoV-2 variates. In spite of B cell maturaion,the uN.1 Omicron varianls, by introducing a single substitution in the S proteln (L455S) compared to its initial subineage, evaded the recently restored lGHV3-53/3-66 germlines. Our work decoded the cryptic role of OAS in COVID-19 and highlights the unceasing interplay between SARS-CoV.2 and the human immune system which may be a never-ending game for the next decades.

嘉宾
Vaccine Innovation Forum World 2025-中文站点
Emanuele Andreano
Project Leader, Fondazione Toscana Life Sciences, Italy
Chair
Vaccine Innovation Forum World 2025-中文站点
杜笑寒
赛诺菲疫苗全球对外研发部资深总监

As Senior Director at Sanofi Vaccines External R&D, Sean is responsible for the identification and evaluation vaccine-related opportunities to support Sanofi Vaccines’ global pipeline strategy. Under his leadership, Sanofi Vaccines has completed three research agreements, initiated over 10 feasibility studies with both academic and industrial partners, organized 4 full due diligence, executed two global licensing agreements with biotech companies, and reached a 280 million AUD collaboration agreement with Queensland State Government. Sean has over 20 years of extensive vaccine R&D and business development experience. Before joining Sanofi, Sean was Co-Founder and Chief Operating Officer at Altravax from 2013 to 2015 and Executive Director & Head of the Vaccine Research Institute at Simcere Pharmaceutical Group from 2010 to 2013. Prior to Simcere, he worked as a Senior Scientist and Project Leader on multiple vaccine programs at Maxygen for 9 years. Sean received his Ph.D. degree in Biological Sciences from the University of Delaware, M.S degree in Microbiology from the Institute of Microbiology, Chinese Academy of Sciences, and B.S. degree in Microbiology from Shandong University. He received his postdoctoral training at Columbia University.

Opening Remark
Vaccine Innovation Forum World 2025-中文站点
王宾
复旦大学特聘教授;艾棣维欣创始人

Dr. Bin Wang is the Co-founder, Chairman of Advaccine Biotechnology Co LTD. He is also holding a distinguished professor position at the Fudan University School of Basic Medical Sciences and serves as the chairman for the Nucleic Acid Vaccines branch of the Chinese Vaccine Society. His research area is focused on the effects of therapeutic vaccination to activate T cells and the mechanism of immune regulations. He has developed novel adjuvants and recombinant vaccines, novel DNA vaccine delivery, and led to several developed vaccines being tested in human clinical trials. He received his Ph.D. from the Cincinnati Children's Hospital at the University of Cincinnati School of Medicine in 1990. He completed his postdoc training in virology and immunology at the Wistar Institute in 1992 in Philadelphia. He became an instructor and assistant professor at the University of Pennsylvania Medical School from 1993 to 1998. He was a professor and served as the Chairman of the Department of Microbiology and Immunology for six years at the College of Biological Sciences, China Agricultural University before he joined Fudan University. He was one of the very early DNA vaccine technology inventors in the 90’s and performed the first-in-human DNA vaccine trials in 1994-1996. He has been involved in several clinical trials of therapeutic vaccines against chronic HBV infections in recent years and invented a novel prophylactic RSV vaccine currently under clinical phase II testing. He has published over 160 peer-review articles and awarded 35 US and 30 Chinese patents. He serves as an editorial board member for several international journals and executive member in several professional societies.

Plenary Panel: Revolutionizing Global Health: The Future of Vaccine Technology and Innovation
Vaccine Innovation Forum World 2025-中文站点
Adrian V. S. Hill
Director, The Jenner Institute, Professor, University of Oxford , UK

Professor Adrian V. S. Hill FRS is the Director and Founder of the Jenner Institute, and Mital Professor of Vaccinology at Oxford University. He is a passionate believer in the power of molecular medicine to address many of the most egregious health care inequities globally. His group have been leaders in the development of adenoviral and other vaccines against infectious diseases and he has tested these in extensively in over eighty clinical trials in Africa and Europe. In partnership with the Serum Institute of India and AstraZeneca the Jenner Institute developed rapidly a ChAdOx1 vector-based SARS-CoV-2 vaccine which saved an estimated 6.2 million lives in 2021 alone.

His lab also designed a newly licensed high efficacy malaria vaccine, R21/Matrix-MTM, which has recently shown unprecedented high efficacy in a phase III trial in four African countries, again in partnership with the Serum Institute of India and also Novavax Inc. This vaccine promises to make a major impact on reducing the 500,000 childhood deaths from malaria each year. In 2021 he was elected a Fellow of the Royal Society and is a Knight Commander of the Order of the British Empire (KBE).


Vaccine Innovation Forum World 2025-中文站点
高福
中科院院士、教授

George Fu Gao has been a key leader in the public health field, making remarkable contributions to research and discovery through basic research, clinical evaluation and advocacy. He has made many remarkable contributions to the scientific field of control and prevention of emerging infectious diseases. He obtained his DPhil degree from Oxford University, UK and did his postdoc work in both Oxford University and Harvard University (with a brief stay in Calgary University). Gao worked in Beijing Agricultural University (1986-1991), Oxford University (2001-2006), Institute of Microbiology, Chinese Academy Sciences (2004-2008, Director-General). China CDC (Director-General, 2017-2022), National Science Foundation of China (Vice-President, 2018-2022). Gao is a member (academician) of Chinese Academy of Sciences (CAS), an international member of the U.S. National Academy of Sciences (NAS), a foreign member of the U.K. Royal Society (RS), a member of the German National Academy of Sciences Leopoldina, a fellow of African Academy of Sciences and a fellow of The World Academy of Sciences (TWAS).


Vaccine Innovation Forum World 2025-中文站点
Dan Barouch
Professor, Harvard Medical School

Dr. Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, a member of the Ragon Institute of MGH, MIT, and Harvard, and part of the Bill & Melinda Gates Foundation Collaboration for AIDS Vaccine Discovery.  His laboratory focuses on studying the immunology and pathogenesis of viral infections and developing novel vaccine and treatment strategies.  His group has led the development of vaccine candidates for multiple pathogens of global significance, including HIV, Zika virus, tuberculosis, and most recently SARS-CoV-2.  His work contributed to the development of the Johnson & Johnson COVID-19 vaccine and the evaluation of multiple COVID-19 vaccines and monoclonal antibody therapeutics.  He was elected to the National Academy of Medicine in 2020 and received the King Faisal Prize in Medicine in 2023.

 


Vaccine Innovation Forum World 2025-中文站点
Francesco Berlanda Scorza
VP R&D, Global Health R&D Vaccines Head and GVGH Institute, GSK, Belgium

Dr. Berlanda Scorza is an accomplished pharmaceutical executive with a strong focus on translating scientific innovations into tangible patient benefits. He currently serves as Vice President of Global Health R&D Vaccines at GSK. Additionally, he is the Chairman of the Board and General Manager of the GSK Vaccines Institute for Global Health, as well as a member of the GSK Country Executive Board in Italy.

Before joining GSK in 2020, Dr. Berlanda Scorza held senior leadership roles at the Bill & Melinda Gates Foundation and PATH, where he led key programs focused on the development of seasonal and pandemic influenza vaccines.

Earlier in his career, Dr. Berlanda Scorza was a senior scientist at Chiron Corporation and Novartis Vaccines, where he contributed to the development of innovative vaccine technologies, including a replicon RNA vaccine, the cell-cultured influenza vaccine Flucelvax, and the bacterial vaccine platform GMMA. Dr. Berlanda Scorza earned his Ph.D. from the University of Milano-Bicocca and completed his post-doctoral research at Imperial College London.


Vaccine Innovation Forum World 2025-中文站点
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany

Ruben Rizzi, physician by training, SVP of Global Regulatory Affairs at BioNTech. I joined the company in December 2019 just before the pandemic, and I have been the global regulatory lead for BioNTech for our COVID-19 development. Currently, I am still supporting the lifecycle of our COVID-19 vaccine, and I am co-leading the Global Regulatory Affairs department at BioNTech and working closely with the teams that are responsible for the development of BioNTech´s pipeline, post-approval activities and labelling


Vaccine Innovation Forum World 2025-中文站点
杜笑寒
赛诺菲疫苗全球对外研发部资深总监

As Senior Director at Sanofi Vaccines External R&D, Sean is responsible for the identification and evaluation vaccine-related opportunities to support Sanofi Vaccines’ global pipeline strategy. Under his leadership, Sanofi Vaccines has completed three research agreements, initiated over 10 feasibility studies with both academic and industrial partners, organized 4 full due diligence, executed two global licensing agreements with biotech companies, and reached a 280 million AUD collaboration agreement with Queensland State Government. Sean has over 20 years of extensive vaccine R&D and business development experience. Before joining Sanofi, Sean was Co-Founder and Chief Operating Officer at Altravax from 2013 to 2015 and Executive Director & Head of the Vaccine Research Institute at Simcere Pharmaceutical Group from 2010 to 2013. Prior to Simcere, he worked as a Senior Scientist and Project Leader on multiple vaccine programs at Maxygen for 9 years. Sean received his Ph.D. degree in Biological Sciences from the University of Delaware, M.S degree in Microbiology from the Institute of Microbiology, Chinese Academy of Sciences, and B.S. degree in Microbiology from Shandong University. He received his postdoctoral training at Columbia University.

Plenary Panel: Global Vaccine Equity: Overcoming Challenges in Distribution and Access
Vaccine Innovation Forum World 2025-中文站点
Rajinder Suri
CEO, DCVMN International, India

Rajinder as CEO-DCVMN International is responsible for leadership, governance, strategic vision and overall operational excellence of DCVMN.  Rajinder is appointed as member GAVI’s Vaccine Investment Strategy (VIS) Steering Committee 2024, a permanent member of CEPI’s Joint Coordination Group (JCG), 2023-24, member PAVMs Talent Development WS and Regional Vaccine Manufacturing Collaborative (RVMC). To meet an un-precedented challenge posed by COVID-19, Rajinder has been actively involved in all global strategic initiatives along with COVAX partners-WHO, GAVI, CEPI, UNICEF and several other international organizations including industry associations to ensure equitable and timely access to vaccines. He has been member of several advisory expert groups including COVAX Manufacturing & Supply Chain Task Force Leadership Team, G-20 Health Working Group and Market Design and Demand Intelligence pillar of PAVM. Rajinder has over 25 years of top management experience in the industry including at the Board of Directors of the Indian subsidiary of Sanofi Pasteur and as CEO-Panacea Biotec. He has served as Member-GAVI-PPC as well as Vice-President, DCVMN Executive Committee.

Vaccine Innovation Forum World 2025-中文站点
Raman Rao
CEO, Hilleman Laboratories

Dr. Raman Rao joined as the Chief Executive Officer at Hilleman Laboratories in February 2020. Dr. Rao has more than two decades of experience in research and development, manufacturing and commercialisation of vaccines for infectious diseases in global pharma and biotech companies. Prior to joining Hilleman Laboratories, Dr. Rao served as the Vice President of Global Product Operations with Takeda, Singapore, where he enhanced the global product portfolio while successfully leading an international team across Japan, Singapore and the United States. The teams worked in the areas of dengue, norovirus, zika, polio and other vaccines.

Dr. Rao started his career in 2002 with Shantha Biotechnics Limited, part of Sanofi Aventis Group in India, in Clinical Research and Scientific Affairs. He holds a MD in Medical Microbiology from the Postgraduate Institute of Medical Education and Research.

He plans to carry forward Dr. Maurice Hilleman’s legacy for providing effective solutions for global health, especially those impacting low- and middle-income countries.


Vaccine Innovation Forum World 2025-中文站点
Hun Kim
President of Global Business, SK Bioscience, South Korea

Dr. Hun Kim is the President of Global Business at SK Bioscience. His role is to oversee the company's product and platform portfolio in a comprehensive perspective from R&D to commercialization through global alliance and external innovation.

Dr. Hun Kim started his biopharmaceutical career in 1992 as a researcher at Green Cross Corporation, In 2000, he moved on to Berna Biotech, a part of Crucell at present. In 2008, he joined SK Chemicals,the parent company of SK Bioscience, and lead the company's expansion in vaccine R&D, Quality and manufacturing capabilities.

Under his oversight, the company developed and received approval for cell culture-based influenza vaccines (SKYCellflu/SKYCellflu Quadrivalent), varicella/herpes zoster vaccines (SKYVaricella/SKYZoster),and Pneumococcal Conjugation Vaccines. During the Pandemic, it successfully manufactured and supplied COVID-19 vaccines developed by AstraZeneca and NovaVax. With support from CEPI and BMGF, SK Bioscience also developed its own COVID-19 vaccine (SKYCovione), which became the first domestically developed COVID-19 vaccine to be approved in Korea.


Vaccine Innovation Forum World 2025-中文站点
王靖
执行董事&首席商务官,康希诺生物,中国

Ms. WANG is responsible for the company's overall commercial operation in both China and Overseas markets. She has 23 years experience in pharmaceutical industry and holds a bachelor degree in Economics, a master degree in engineering of Peking University and Global EMBA of CEIBS. Jeanne joined the Company in 2012 and made outstanding achievements in multiple roles such as Head of HR, Head of Operation, Vice President of Strategy & Business Development and Chief Financial Officer. She helped the company set up the management system of financing, financial operations, human resources and commercialization. After completing several rounds of Pre-IPO fund raising, Ms. Wang also successfully led the Company’s IPO on Main Board of Hong Kong Stock Exchange in 2019 and on the Sci-tech Innovation Board of the Shanghai Stock Exchange in 2020, making the Company the first “A+H” dual listing vaccine company.


Vaccine Innovation Forum World 2025-中文站点
梁晓峰
中国预防医学会副会长,暨南大学教授

主任医师,暨南大 学讲席教授。暨南大学疫苗产业研究院/疾病预防控制研究院院长。曾任中国疾控中心副主任。现在兼任中国卫生有害生物防制协会会长、中华预防医学会副会长,世界卫生组织病毒性肝炎防控委员会委员、西太区免疫接种技术委员会委员、世界公共卫生联盟执委、中华预防医学会医疗机构公共卫生管理分会主任委员等职务。

主要从事疫苗接种,传染病控制,慢性病危险因素监测和疾病负担研究。承担传染病防治科技重大专项“乙型肝炎病毒免疫预防新策略的研究”研究。作为第一作者和责任作者,分别在新英格兰杂志、柳叶刀和疫苗杂志发表多篇学术论文。

 获得了国务院特贴和卫生部有突出贡献中青年专家称号。2013年获得“吴阶平杨森医学药学奖”。2014年,“我国首次对甲型H1N1流感大流行有效防控及集成创新性研究”获得国家科技进步一等奖。2023年选为“广东省重大人才工程项目杰出人才”。2024年获广东省疾控中心高层次引进人才。


茶歇
Keynote: Innovative Vaccine Platforms: Accelerating Global Health R&D
Vaccine Innovation Forum World 2025-中文站点
Francesco Berlanda Scorza
VP R&D, Global Health R&D Vaccines Head and GVGH Institute, GSK, Belgium

Dr. Berlanda Scorza is an accomplished pharmaceutical executive with a strong focus on translating scientific innovations into tangible patient benefits. He currently serves as Vice President of Global Health R&D Vaccines at GSK. Additionally, he is the Chairman of the Board and General Manager of the GSK Vaccines Institute for Global Health, as well as a member of the GSK Country Executive Board in Italy.

Before joining GSK in 2020, Dr. Berlanda Scorza held senior leadership roles at the Bill & Melinda Gates Foundation and PATH, where he led key programs focused on the development of seasonal and pandemic influenza vaccines.

Earlier in his career, Dr. Berlanda Scorza was a senior scientist at Chiron Corporation and Novartis Vaccines, where he contributed to the development of innovative vaccine technologies, including a replicon RNA vaccine, the cell-cultured influenza vaccine Flucelvax, and the bacterial vaccine platform GMMA. Dr. Berlanda Scorza earned his Ph.D. from the University of Milano-Bicocca and completed his post-doctoral research at Imperial College London.


Correlates of Protection for Respiratory Virus Vaccines
Vaccine Innovation Forum World 2025-中文站点
Dan Barouch
Professor, Harvard Medical School

Dr. Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, a member of the Ragon Institute of MGH, MIT, and Harvard, and part of the Bill & Melinda Gates Foundation Collaboration for AIDS Vaccine Discovery.  His laboratory focuses on studying the immunology and pathogenesis of viral infections and developing novel vaccine and treatment strategies.  His group has led the development of vaccine candidates for multiple pathogens of global significance, including HIV, Zika virus, tuberculosis, and most recently SARS-CoV-2.  His work contributed to the development of the Johnson & Johnson COVID-19 vaccine and the evaluation of multiple COVID-19 vaccines and monoclonal antibody therapeutics.  He was elected to the National Academy of Medicine in 2020 and received the King Faisal Prize in Medicine in 2023.

 


AI-Guided and Structure-Based Vaccine Design
Vaccine Innovation Forum World 2025-中文站点
高福
中科院院士、教授

George Fu Gao has been a key leader in the public health field, making remarkable contributions to research and discovery through basic research, clinical evaluation and advocacy. He has made many remarkable contributions to the scientific field of control and prevention of emerging infectious diseases. He obtained his DPhil degree from Oxford University, UK and did his postdoc work in both Oxford University and Harvard University (with a brief stay in Calgary University). Gao worked in Beijing Agricultural University (1986-1991), Oxford University (2001-2006), Institute of Microbiology, Chinese Academy Sciences (2004-2008, Director-General). China CDC (Director-General, 2017-2022), National Science Foundation of China (Vice-President, 2018-2022). Gao is a member (academician) of Chinese Academy of Sciences (CAS), an international member of the U.S. National Academy of Sciences (NAS), a foreign member of the U.K. Royal Society (RS), a member of the German National Academy of Sciences Leopoldina, a fellow of African Academy of Sciences and a fellow of The World Academy of Sciences (TWAS).


午餐
Chair
Vaccine Innovation Forum World 2025-中文站点
舒跃龙
中国医学科学院病原生物学研究所所长、教授

Prof. Yuelong Shu

Director, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College. He is a member of the Chinese Academy of Medical Sciences and a Fellow of the American Academy of Microbiology. He was selected as the first batch of ‘National Science and Technology Innovation Leader’and‘2014 Top Ten Scientific and Technological Innovators’, and is the winner of National Science Fund for Distinguished Young Scholars and the China Youth Science and Technology Award. He has been honored with the National Science and Technology Progress Grand Prize, First Prize, Second Prize, the National Medical and Health System Advanced Individual, the National Innovation Award, the Public Health and Preventive Medicine Development Contribution Award, etc. He is currently the Chairman of the Branch of Medical Virology of the Chinese Medical Association and the Chairman of the Asia-Pacific Alliance for the Control of Influenza (APACI). He was the founding dean of the School of Public Health of Sun Yat-sen University (Shenzhen), the editor-in-chief of the Chinese Journal of Virology, the deputy director of the Institute of Viral Diseases of the Chinese Center for Disease Control and Prevention (CDC), the director of the National Influenza Center, and the director of the WHO Collaborating Center for Reference and Research on Influenza.

Shu has long focused on influenza prevention and control research, and has made outstanding achievements in the discovery of new viruses, the development of detection reagents, and the pathogenesis of infection. Through the systematic establishment of new influenza detection and surveillance technology, it was found for the first time in the world that a variety of new avian influenza viruses such as H7N9, H5N6 and H10N8 can lead to human infection and death; The first successful development of pandemic H1N1 2019 and H7N9 avian influenza detection reagent; The origin, evolution and infection mechanism of H7N9 and other avian influenza viruses were clarified, which provided key scientific and technological support for the successful prevention and control of the epidemic in China. He has published nearly 200 papers in Science, Nature, NEJM, Lancet and other academic journals as a corresponding author. The research results were selected as one of the ‘China’s 100 most influential international academic papers in 2013’and ‘2013 Top Ten Scientific Advances in China’.


Pan-sarbeCoV vaccine: a dream or reality?
Vaccine Innovation Forum World 2025-中文站点
王林发
杜克-新加坡国立大学医学院教授

Dr. Linfa Wang is a professor of the Programme in Emerging Infectious Diseases at Duke-NUS Medical School, and the inaugural executive director of PREPARE, Ministry of Health, Singapore. He is an international leader in the field of emerging zoonotic viruses and virus-host interaction. In response to the COVID-19 pandemic, he has served and is serving on multiple WHO committees for COVID-19, including the WHO IHR Emergency Committee. Prof. Wang has more than 500 scientific publications. He was the Editor-in-Chief for the Virology Journal from 2112-2022. Prof. Wang was elected to the Australian Academy of Technological Sciences and Engineering in 2010, the American Academy of Microbiology in 2021 and the Australian Academy of Sciences in 2023. He received the Singapore President Science Award in 2021

mRNA Vaccines in Low- and Middle-Income Countries: Bridging the Gap
Vaccine Innovation Forum World 2025-中文站点
Kiat Ruxrungtham
Director of Chula Vaccine Research Center, Chulalongkorn University
Kiat Ruxrungtham, is a Professor of Medicine, Department of Medicine , Faculty of Medicine, Chulalongkorn University; and Scientific Chair of the Chula Vaccine Research Center (ChulaVRC); and Director of the Covid19 Vaccine Development Program, ChulaVRC. He is providing teaching and patient care on Allergy -Clinical Immunology and HIV Medicine at the King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University; and is mentoring junior researchers on HIV medicine at HIVNAT, TRCARC; vaccine and Immunology (at Chula Vaccine Research Center); and also on clinical trials. He is currently leading the Chula-Covid19 mRNA vaccine development program at ChulaVRC. Honors: He has received several awards: 2006 Outstanding Internist Award on Medical Academy, Royal College of Physicians, Thailand 2007 Outstanding Researcher Award, and the Highest Citation Award, Chulalongkorn University, Bangkok, Thailand 2011 Senior Research Scholar Award, the Thailand Research Fund 2011 Outstanding Researcher Award, National Research Council, Thailand 2015 Senior Research Scholar Award, the Thailand Research Fund 2015 Outstanding Research Award, the Thailand Research Fund 2022 A Royal Award “Contributors to the development of the country’s vaccines” from Her Royal Highness Princess Maha Chakri Sirindhorn at the 10th Vaccination Conference Publications: He has published more than 370 peer review papers on HIV, immunology, allergy, and vaccine. Contributions to national and international academics and professional organization: 1. Former President of the Allergy, Asthma and Immunology Association, Thailand (AAIAT) 2. Former President of the Thai AIDS Society (TAS) 3. Co-chair of the Co-chair of the APAACI and APAAAPARI 2018, Bangkok, Thailand 4. Co-chair of the World Allergy Congress 2023, Bangkok, Thailand 5. Chief-editor, Asian Pacific Journal of Allergy and Immunology (APJAI)
Impact of glycosylation on a broad-spectrum vaccine against influenza
Vaccine Innovation Forum World 2025-中文站点
陳俊叡
润惠生技运营长,中国

Dr. Chen is a prominent scientist specializing in human vaccine research and antiviral therapies. He currently serves as the Chief Operating Officer at RuenHuei Biopharmaceuticals Inc., where he oversees the development and production of new vaccine candidates. Dr. Chen joined RH Biopharma in August 2018, bringing over a decade of practical industry experience in vaccine development. Before his role at RH Biopharma, Dr. Chen held several key positions at Adimmune Corporation, including the Director and Manager of the R&D Department. At Adimmune, he was instrumental in developing the EV71 vaccine and advancing a cell culture-based production process for influenza vaccines. Dr. Chen's academic background includes a Ph.D. from National Yang-Ming University in Taipei, Taiwan, where he specialized in Biochemistry and Molecular Biology. He also completed postdoctoral fellowships at the Genomics Research Center, Academia Sinica, and the Vollum Institute at Oregon Health and Science University in the United States. His research has significantly contributed to the field of vaccine development, particularly in creating more effective influenza vaccines and understanding the immune responses to viral infections. He is currently also special technical expert at the Department of Pharmacy at National Taiwan University and an associate professor at the Department of Chemistry at National Chung Hsing University

A New Strategy for Vaccine Immune Evaluation System
Vaccine Innovation Forum World 2025-中文站点
Chongyang Liang
Prof., Jilin University;Scientific Advisor, ProMab Forethought;

梁重阳教授专注于重组蛋白大分子药物开发领域,多年从事药物作用机制相关结构生物学研究及理化分析工作,主导研发多项创新型单抗药物和亚单位疫苗,通过成果转化与企业合作推动管线在美国FDA和中国NMPA获批临床试验或上市。


General Considerations for the Non-clinical Safety Evaluation of Preventive mRNA Vaccines
Vaccine Innovation Forum World 2025-中文站点
胡颖
毒理二部主任, 昭衍(苏州)新药研究中心有限公司

胡颖

昭衍(苏州)新药研究中心有限公司,毒理二部主任

 

中国认证毒理学家(DCST),中国毒理学会生殖毒理专业委员会青年委员。本科和研究生曾就读于扬州大学兽医学院,硕士学位。从事药物毒理安全性评价工作14+,作为专题负责人完成550+项非临床毒理学研究,包括一般毒理、生殖和发育毒理、幼龄动物毒理试验、致癌性试验等。主要业务方向包括小分子化药、单克隆抗体/双特异性抗体、融合蛋白、多肽、疫苗、小核酸药物等。


茶歇
Decoding Antibody Response to MERS-CoV in Wild Dromedary Camels
Vaccine Innovation Forum World 2025-中文站点
张林琦
清华大学教授

Professor Linqi Zhang is the Director of the Comprehensive AIDS Research Center at Tsinghua University. Prof. Zhang's research focuses on HIV-1 pathogenesis and vaccine development, and has recently expanded to the field of emerging and re-emerging human viral pathogens such as SARS-CoV-1/2 and MERS-CoV. Using cutting-edge antibody and combinatorial antigen library techniques, Prof. Zhang’s research aims to characterize protective antibody immunity in infected humans and rational design of effective vaccines and therapies against the viral infection. Professor Zhang is the recipient of the National Outstanding Young Scientist Award, privileged Changjiang Professorship, and Bayer and Vanke Chair professor. He has published extensively and is among the most cited Chinese researchers in the field of microbiology and immunology. Professor Zhang has also served as a member of national expert and advisory board to the Chinese government and several international organizations on HIV/AIDS and infectious diseases,and was recently elected as a Foreign Fellow of the African Academy of Sciences.

Vaccine Clinical Trials: Practical Insights to Avoid Pitfalls
Vaccine Innovation Forum World 2025-中文站点
莫兆军
斯丹姆医药疫苗临床业务/上海斯丹姆总经理

-17年疫苗临床行业经验 n前广西疾控疫苗临床研究所所长(2010-2022),管理和实施过近300个临床试验,70+个疫苗临床试验PI,多个大型疫苗多中心效力试验leading PI。 

-CDE药审专家和国家专班专家,曾参与编著和讨论多个国家疫苗临床试验相关法规、技术指导原则,多次参加重大新药创制科技重大专项课题。 n曾作为PI主持:全球首个人二倍体细胞EV71灭活疫苗、国内首个mRNA新冠疫苗、HPV疫苗、轮状病毒疫苗、微卡、狂犬疫苗、IPV、bOPV、流感、肺炎疫苗、流脑疫苗等。 

-在国际期刊发表30+篇SCI论著,疫苗学第七版翻译编委、预防性疫苗临床试验设计与实施编委。 

-曾任国家局药品注册审评专家委员会委员、国务院联防联控机制科研攻关组疫苗研发专班专家组成员、国家免疫规划技术工作组成员、中华预防医学会疫苗临床专业委员会常委、原国家级和省级GCP检查员。

Clinical development for RSV vaccine in China
Vaccine Innovation Forum World 2025-中文站点
谭巍
三叶草生物高级副总裁,中国研发及外部合作负责人

Dr. Tan is responsible for drug discovery, preclinical development, translation research and external collaboration in China. Dr. Tan got his Ph.D. in Molecular Medicine from UT Health Science Center San Antonio and received his Postdoctoral training with Dr. Michael Karin at UC San Diego. Dr. Tan worked in Pfizer and Novartis for 9 years, specialized in drug discovery and translational research, bridging preclinical research to early clinical trials. Dr. Tan worked at Biosion Biotech and Coherent Biopharma before he joined Clover. Dr. Tan was selected as Jiangsu Innovation and Entrepreneur Talent and Suzhou Innovation and Entrepreneur Leading Talent.

Pan-β-coronavirus vaccine development
Vaccine Innovation Forum World 2025-中文站点
姜世勃
复旦大学教授

Dr. Shibo Jiang is a Professor at the Shanghai Institute of Infectious Disease and Biosecurity of Fudan University, Shanghai, China. His main research interest is the development of antiviral drugs and vaccines. He has published 572 papers (total IF: 7,662, average IF: 13.4) in SCI journals such as Cell (x3), Nature (x2), Science (x2), Lancet (x4), CNS’ sister journals (x71), with total 45,327 citations and an h-index of 105. He has applied for 104 patents, 54 of which were issued, and 11 of them were licensed out with 3 classes of innovative drugs and medical products used in clinics.

Poster Session
Welcome Cocktail Party (Invited only)
Chair
Vaccine Innovation Forum World 2025-中文站点
王宾
复旦大学特聘教授;艾棣维欣创始人

Dr. Bin Wang is the Co-founder, Chairman of Advaccine Biotechnology Co LTD. He is also holding a distinguished professor position at the Fudan University School of Basic Medical Sciences and serves as the chairman for the Nucleic Acid Vaccines branch of the Chinese Vaccine Society. His research area is focused on the effects of therapeutic vaccination to activate T cells and the mechanism of immune regulations. He has developed novel adjuvants and recombinant vaccines, novel DNA vaccine delivery, and led to several developed vaccines being tested in human clinical trials. He received his Ph.D. from the Cincinnati Children's Hospital at the University of Cincinnati School of Medicine in 1990. He completed his postdoc training in virology and immunology at the Wistar Institute in 1992 in Philadelphia. He became an instructor and assistant professor at the University of Pennsylvania Medical School from 1993 to 1998. He was a professor and served as the Chairman of the Department of Microbiology and Immunology for six years at the College of Biological Sciences, China Agricultural University before he joined Fudan University. He was one of the very early DNA vaccine technology inventors in the 90’s and performed the first-in-human DNA vaccine trials in 1994-1996. He has been involved in several clinical trials of therapeutic vaccines against chronic HBV infections in recent years and invented a novel prophylactic RSV vaccine currently under clinical phase II testing. He has published over 160 peer-review articles and awarded 35 US and 30 Chinese patents. He serves as an editorial board member for several international journals and executive member in several professional societies.

Immunotherapy for Cancer
Vaccine Innovation Forum World 2025-中文站点
David Weiner
Executive Vice President, The Wistar Institute, USA

Dr. David Weiner directs a translational research laboratory at The Wistar Institute in the area of Molecular Immunology. His group is one of the pioneering research teams in establishing the field of DNA vaccines and immunotherapies. Important reports from his lab include the first DNA vaccine studied for HIV as well as for cancer immunotherapy, the early development of DNA encoded genetic adjuvants including the particularly relevant IL-12, advances in gene optimization, and advances in electroporation (EP) technologies resulting in improved gene delivery among others. His group worked with collaborators to become the first to move DNA technology into human study. His laboratory’s work helped revitalize the field through advancement of new synthetic DNA design and modification of EP delivery approaches resulting in potent immune induction as well as the first successful Phase IIb DNA efficacy study (for HPV immunotherapy) in humans. Dr. Weiner is the recipient of numerous honors including election as a fellow to both the American Association for the Advancement of Science in 2011 and the International Society for Vaccines in 2012. He is the recipient of the NIH Director’s Transformative Research Award and received the Vaccine Industry Excellence Award for Best Academic Research Team in 2015 at the World Vaccine Congress. Weiner was honored with the prestigious Hilleman Lectureship in 2015 at the Children’s Hospital of Philadelphia Grand Rounds session and received a Stone Family Award from Abramson Cancer Center for his groundbreaking work on DNA vaccines for cancer immunotherapy. In 2019, Dr. Weiner was honored with the Scientific Achievement Award from Life Sciences PA (LSPA). Dr. Weiner returned to Wistar in 2016 from his position at The University of Pennsylvania School of Medicine as professor of Pathology and Laboratory Medicine. From 1990 to 1993, Weiner held a joint position as assistant professor of Pathology and Laboratory Medicine at The Wistar Institute and the University of Pennsylvania School of Medicine. Dr. Weiner is a co-founder of Inovio Pharmaceuticals and is a member of the Board of Directors. Dr. Weiner graduated with a B.S. in biology from SUNY at Stony Brook, N.Y., a M.S. in biology from the University of Cincinnati and a Ph.D. in developmental biology from the University of Cincinnati College of Medicine.

Development of mRNA vaccines: from infectious diseases to oncology
Vaccine Innovation Forum World 2025-中文站点
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany

Ruben Rizzi, physician by training, SVP of Global Regulatory Affairs at BioNTech. I joined the company in December 2019 just before the pandemic, and I have been the global regulatory lead for BioNTech for our COVID-19 development. Currently, I am still supporting the lifecycle of our COVID-19 vaccine, and I am co-leading the Global Regulatory Affairs department at BioNTech and working closely with the teams that are responsible for the development of BioNTech´s pipeline, post-approval activities and labelling


Expanding the Frontier: mRNA Vaccines for Cancer and Autoimmune Diseases(TBD)
Vaccine Innovation Forum World 2025-中文站点
英博
创始人,董事长兼首席执行官,艾博生物

英博博士于2019年创立艾博生物,为公司创始人、董事长兼首席执行官。创立至今,艾博生物已建立起具有自主知识产权的mRNA和纳米递送技术平台,推动mRNA科学技术应用赋能创新医疗产品开发。


英博博士拥有国际化的行业视野和丰富的核酸药物开发领域工业界经验,精通RNA药物设计和纳米制剂产业化。创立艾博生物前,他曾在多家全球领先的核酸药物研发机构任核心研发团队负责人,领导开展包括小核酸(siRNA)、mRNA及基因编辑产品的开发及大规模工业化生产等工作。

英博博士本科、硕士毕业于复旦大学,并在美国东北大学获得药剂学博士学位。英博博士曾在Cell、Lancet等多个重要国际期刊发表论文,他也是多项海外授权专利发明人。2018-2019年期间,英博博士任波士顿美中生物医药协会(Chinese-American BioMedical Association)会长,服务生物医药科研和工业技术的深度融合。

SynNeogen: unleash the power of immune system
Vaccine Innovation Forum World 2025-中文站点
陆汉新
凯米生物研发副总裁

陆汉新博士获乔治华盛顿大学遗传学博士学位,在生物医药产品开发领域拥有16年开拓性经验。他领导多学科团队推动治疗性与预防性疫苗技术平台创新,其开创性工作涵盖两大方向:开发针对高胆固醇血症等代谢紊乱及神经退行性病变的免疫治疗疫苗;设计新一代疫苗以应对呼吸道合胞病毒(RSV)、大流行流感、埃博拉病毒等新发传染性病原体。

陆博士的科学领导力贯穿疫苗研发全链条:从发现阶段的靶点验证、理性抗原设计及佐剂优化,到临床前开发的动物模型开发、机制研究与药效学分析,到生物标志物分层指导的I-III期临床试验,以及病毒学特性表征及符合GLP规范的疗效/安全性评估。


Precision treatment of pancreatic cancer - personalized tumor treatment vaccine
Vaccine Innovation Forum World 2025-中文站点
胡兰靛
深圳安达生物CEO

Doctor Hu is the founder, chairman and full-time CEO of Anda Biology. She was a former researcher of the Chinese Academy of Sciences Shanghai Institute of Nutrition and Health, visiting scholar of the Max-Planck-Institute for Molecular Genetics in Germany, and visiting scholar of the Cambridge Molecular Biology Laboratory in the UK. She independently undertook key projects of the National Natural Science Foundation of China and 863 projects as the project leader, participated in the Super 973 projects, the Chinese Academy of Sciences' Leading Special Research on Stem Cell and Regenerative Medicine, and the National Twelfth Five Year Plan Major Special Projects. Expert in the Second Review of Outstanding Youth Fund, Outstanding Youth Fund, and Key Projects of the National Natural Science Foundation of China, and expert in risk assessment of the Ministry of Science and Technology in 2013.

She has been engaged in molecular genetics research of diseases for a long time and has established a series of genetic analysis techniques that can be applied to stem cell clinical transformation research such as stem cell quality control, in vivo genetic tracing, stem cell maintenance, and cell phenotype transformation, laying the foundation for stem cell based disease diagnosis and treatment. Dr Hu has published more than 70 SCI papers and won the first prize for scientific and technological progress in Shanghai (second place completion).

 

She has participated as the leader of the innovation team in 2018 in the first Shenzhen Women's Innovation and Entrepreneurship Competition. After winning the award, she founded Anda Biology Medicine Development (Shenzhen) Co., Ltd and she is serving as its full-time CEO. In the past four years, she has led the company's employees to develop personalized immunotherapy vaccine for pancreatic cancer, universal cancer vaccines, cell therapy and other products. Among which, PCNAT-1, a therapeutic personalized vaccine for pancreatic cancer, has won the FDA orphan drug qualification certification.


茶歇
Induction of tertiary lymphatic structures (TLS) by a novel immunotherapeutic strategy against solid tumors
Vaccine Innovation Forum World 2025-中文站点
王宾
复旦大学特聘教授;艾棣维欣创始人

Dr. Bin Wang is the Co-founder, Chairman of Advaccine Biotechnology Co LTD. He is also holding a distinguished professor position at the Fudan University School of Basic Medical Sciences and serves as the chairman for the Nucleic Acid Vaccines branch of the Chinese Vaccine Society. His research area is focused on the effects of therapeutic vaccination to activate T cells and the mechanism of immune regulations. He has developed novel adjuvants and recombinant vaccines, novel DNA vaccine delivery, and led to several developed vaccines being tested in human clinical trials. He received his Ph.D. from the Cincinnati Children's Hospital at the University of Cincinnati School of Medicine in 1990. He completed his postdoc training in virology and immunology at the Wistar Institute in 1992 in Philadelphia. He became an instructor and assistant professor at the University of Pennsylvania Medical School from 1993 to 1998. He was a professor and served as the Chairman of the Department of Microbiology and Immunology for six years at the College of Biological Sciences, China Agricultural University before he joined Fudan University. He was one of the very early DNA vaccine technology inventors in the 90’s and performed the first-in-human DNA vaccine trials in 1994-1996. He has been involved in several clinical trials of therapeutic vaccines against chronic HBV infections in recent years and invented a novel prophylactic RSV vaccine currently under clinical phase II testing. He has published over 160 peer-review articles and awarded 35 US and 30 Chinese patents. He serves as an editorial board member for several international journals and executive member in several professional societies.

mRNA Vaccine Platform Technologies with Good Efficacy, Safety and Stability Validated in Several Clinical Trials
Vaccine Innovation Forum World 2025-中文站点
宋相容
威斯津生物创始人总经理

Xiangrong Song is a full professor at Sichuan University and a pharmaceutical scientist at National Key Laboratory of Biotherapy. The Song lab has developed the targeted delivery systems for gene drugs and small molecules to treat tumors, atherosclerosis, ocular diseases, infection or brain diseases. Two novel drug candidates (IND) have been approved for phase I clinical trials. She has authored more than 100 papers and is an inventor of more than 50 issued / pending patents worldwide. The technologies that Dr. Song and her colleagues have developed formed the basis for the launch of 2 biotechnology companies. The two companies are translating the aforementioned academic innovations toward commercialization and societal impact. In 2019, she was a recipient of the first prize of Science and Technology Award in Chinese National Medicine Association, for the research on immune function of Yi nationality's medicine. In 2022, she was named as the elite of science and technology in China.

A therapeutic cancer vaccine platform enhancing cross-presentation and CD8+ CTL response through targeting dendritic cell cytosol
Vaccine Innovation Forum World 2025-中文站点
Joon Haeng Rhee
Professor, Chonnam National University Medical School, South Korea

Dr. Joon Haeng Rhee is a graduate of Chonnam National University Medical School and received PhD from the same university. He has been working on molecular microbial pathogenesis and vaccine biology for more than 30 years. His team was the first reporter of the whole genome sequence of V. vulnificus, which became one of the most widely used standard strains in the Vibrio research field. Vaccine study was first started aiming the high mortality V. vulnificus infections. During the vaccine research, his team came across the finding that a flagellin protein of V. vulnificus has an excellent mucosal adjuvant activity in late 1990s. Now flagellin is applied to the development of effective vaccines and immunotherapeutics against diverse diseases such as cancers, allergies, and Alzheimer’s disease. He served the president of Korean Vaccine Society (KVS) from 2013 to 2015. He was elected as an ISV Fellow and serves a member of ISV Executive Board. He is currently the director of Clinical Vaccine R&D Center and Combinatorial Tumor Immunotherapy Research Center of Chonnam National University. As of November 2023, he has more than 170 papers published in peer-reviewed journals and named as an inventor on 40 patents.

Chair
Vaccine Innovation Forum World 2025-中文站点
Rajinder Suri
CEO, DCVMN International, India

Rajinder as CEO-DCVMN International is responsible for leadership, governance, strategic vision and overall operational excellence of DCVMN.  Rajinder is appointed as member GAVI’s Vaccine Investment Strategy (VIS) Steering Committee 2024, a permanent member of CEPI’s Joint Coordination Group (JCG), 2023-24, member PAVMs Talent Development WS and Regional Vaccine Manufacturing Collaborative (RVMC). To meet an un-precedented challenge posed by COVID-19, Rajinder has been actively involved in all global strategic initiatives along with COVAX partners-WHO, GAVI, CEPI, UNICEF and several other international organizations including industry associations to ensure equitable and timely access to vaccines. He has been member of several advisory expert groups including COVAX Manufacturing & Supply Chain Task Force Leadership Team, G-20 Health Working Group and Market Design and Demand Intelligence pillar of PAVM. Rajinder has over 25 years of top management experience in the industry including at the Board of Directors of the Indian subsidiary of Sanofi Pasteur and as CEO-Panacea Biotec. He has served as Member-GAVI-PPC as well as Vice-President, DCVMN Executive Committee.

Vaccine Innovation Forum World 2025-中文站点
王子龙
董事会高级顾问,沃森生物,中国

Andrew Wong is a highly experienced professional with a strong background in biotech, vaccine development, and business management. Currently serving as the Senior Advisor to the Board of Directors at Walvax, Andrew has made significant contributions to the company's global operations.

Before taking on this advisory role, he was the General Manager of Shanghai Wotai Biotechnology Co., Ltd. from 2019, where he led a global team of over 50 professionals. His team was responsible for global vaccine registration, sales, marketing, technology transfer, and business development. Under his leadership, the team became one of China's leading vaccine export groups, expanding into 21 foreign markets such as Egypt, Morocco, Indonesia, and Thailand. His efforts led to a remarkable 25% compound annual growth rate in vaccine exports over the past five years.

Andrew's tenure at Walvax also includes an eight-year stint as Vice President of Corporate Strategy and Business Development at Shanghai Zerun Biotechnology Co., Ltd. From 2015 to 2020, he played a crucial role in securing major research and development grants, including a $7.5 million funding from the Bill and Melinda Gates Foundation for the development of HPV vaccines. Additionally, he was instrumental in securing R&D grants for Covid-19 vaccines, totaling $26 million from the Gates Foundation and the Coalition for Epidemic Preparedness Innovations (CEPI).

Andrew's academic background includes training in medicine and immunology (MSc) at West China Medical University (now Sichuan University), molecular biology (MSc) at the University of Manitoba, and an MBA from UCLA Anderson School of Management. His 30-year career includes about 12 years of experience at Amgen Inc., where he contributed to the development of recombinant antibody therapeutics and anticancer drugs. With his extensive experience in biotech, vaccine research, and global business development, Andrew Wong has been a driving force in Walvax’s global expansion and success in the vaccine market.


Strengthening Vaccine Manufacturing Capacity in Developing Countries: The Role of DCVMN
Vaccine Innovation Forum World 2025-中文站点
Rajinder Suri
CEO, DCVMN International, India

Rajinder as CEO-DCVMN International is responsible for leadership, governance, strategic vision and overall operational excellence of DCVMN.  Rajinder is appointed as member GAVI’s Vaccine Investment Strategy (VIS) Steering Committee 2024, a permanent member of CEPI’s Joint Coordination Group (JCG), 2023-24, member PAVMs Talent Development WS and Regional Vaccine Manufacturing Collaborative (RVMC). To meet an un-precedented challenge posed by COVID-19, Rajinder has been actively involved in all global strategic initiatives along with COVAX partners-WHO, GAVI, CEPI, UNICEF and several other international organizations including industry associations to ensure equitable and timely access to vaccines. He has been member of several advisory expert groups including COVAX Manufacturing & Supply Chain Task Force Leadership Team, G-20 Health Working Group and Market Design and Demand Intelligence pillar of PAVM. Rajinder has over 25 years of top management experience in the industry including at the Board of Directors of the Indian subsidiary of Sanofi Pasteur and as CEO-Panacea Biotec. He has served as Member-GAVI-PPC as well as Vice-President, DCVMN Executive Committee.

Overview of HPV vaccine development and global vaccine introduction status
Vaccine Innovation Forum World 2025-中文站点
Peter Dull
Deputy Director, Gates Foundation, USA

Peter Dull is the deputy director for Integrated Clinical Vaccine Development within the Global Health Division. In this role, he provides technical and strategic guidance on clinical development to the foundation’s program strategy teams, including Pneumonia and Enteric and Diarrheal Diseases, and external partners. In addition, he leads the foundation’s vaccine development activities for HPV vaccines, including efforts with reduced dose schedules.

Peter joined the foundation in 2014 after 10 years at Novartis Vaccines and Diagnostics where he was the clinical franchise head for Meningitis and Sepsis Vaccines. During that time, he led the clinical development and global licensure for a quadrivalent meningococcal glycoconjugate vaccine (Menveo; MenACWY-CRM) as well as a protein-based serogroup B meningococcal vaccine (Bexsero; 4CMenB). His work also included early clinical development of Group B strep glycoconjugate and Staph aureus vaccines. Prior to joining Novartis, he was an epidemic intelligence service officer in the Meningitis and Special Pathogens Branch at the U.S. Centers for Disease Control and completed subspecialty training in infectious diseases at Emory University.

He received his medical degree at University of Wisconsin-Madison and Internal Medicine training at Oregon Health Sciences University.


China Vaccine Industry Overview
Vaccine Innovation Forum World 2025-中文站点
袁瑗
中国国家代表, PATH

袁瑗女士是帕斯适宜卫生科技组织(PATH)上海代表处中国国家代表。她负责管理PATH与中国伙伴的合作关系,并为PATH在中国提供管理和业务发展支持。她于2007年1月加入PATH,担任过包括项目管理、行政财务官员等多项职务,在疫苗领域从业18年间,参与了乙脑疫苗世卫组织预认证、轮状疫苗开发、肺炎结合疫苗开发和培训、OPV海外临床、Sabin IPV D抗原国际标准制定、HPV疫苗预认证等项目,熟悉疫苗生命周期的生产、质量、临床、药政、药物警戒、生物安全等多个方面。2023年1月,袁瑗女士被选举为中国疫苗行业协会疫苗国际合作促进分会第一任秘书长。在加入PATH之前,她在新加坡Integrity Metals公司担任项目经理并在印尼工作。袁女士在北京大学获得文学学士、工商管理硕士和公共卫生硕士学位。


BioKangtai’s Strategy and Technology Transfer Practices in the Era of Global Vaccine Cooperation
Vaccine Innovation Forum World 2025-中文站点
张骞
康泰生物国际业务部总经理

张骞,深圳康泰生物国际事业部总经理,中国疫苗行业协会疫苗国际合作促进分会委员,毕业于同济大学经管学院和法国ESSEC商学院,负责公司国际商务拓展、国际注册和国际合作工作。曾成功引进包括人二倍体细胞狂犬疫苗生产技术、灭活脊灰疫苗生产技术等多个核心疫苗生产技术。同时与多个新兴市场国家开展了产品海外商务拓展、注册和申报工作,已向东南亚、南亚、中东等国家出口部分产品的成品和中间产品,并正在推进在东南亚、南亚、中东、拉丁美洲、独联体、非洲等国家的成品注册、原液分装和技术转移工作。同时与驻华使领馆、跨国药企、国际研究所、国际组织等展开了丰富的交流与合作。


茶歇
Development of the vaccine production facility and tech transfer in Latin America
Vaccine Innovation Forum World 2025-中文站点
Adel Sattarova
Head of Project Management Department, FSUE SPbSRIVS FMBA of Russia

Ms Adel Sattarova holds Specialist Degree in Pharmacy. She has been working at the Saint Petersburg Scientific Research Institute of Vaccines and Serums (FSUE SPbSRIVS FMBA of Russia) since 2016 and currently holds a Head of Project Management Department position. Ms Adel Sattarova has an experience in regulatory affairs, leads the projects, one of which is the WHO prequalification of the influenza vaccine FLU-M® – the product developed and produced by FSUE SPbSRIVS FMBA of Russia with a production site in Saint Petersburg, Russia and Managua, Nicaragua.


Future prospects for vaccine R&d and manufacturing
Vaccine Innovation Forum World 2025-中文站点
Hun Kim
President of Global Business, SK Bioscience, South Korea

Dr. Hun Kim is the President of Global Business at SK Bioscience. His role is to oversee the company's product and platform portfolio in a comprehensive perspective from R&D to commercialization through global alliance and external innovation.

Dr. Hun Kim started his biopharmaceutical career in 1992 as a researcher at Green Cross Corporation, In 2000, he moved on to Berna Biotech, a part of Crucell at present. In 2008, he joined SK Chemicals,the parent company of SK Bioscience, and lead the company's expansion in vaccine R&D, Quality and manufacturing capabilities.

Under his oversight, the company developed and received approval for cell culture-based influenza vaccines (SKYCellflu/SKYCellflu Quadrivalent), varicella/herpes zoster vaccines (SKYVaricella/SKYZoster),and Pneumococcal Conjugation Vaccines. During the Pandemic, it successfully manufactured and supplied COVID-19 vaccines developed by AstraZeneca and NovaVax. With support from CEPI and BMGF, SK Bioscience also developed its own COVID-19 vaccine (SKYCovione), which became the first domestically developed COVID-19 vaccine to be approved in Korea.


Innovative products for low resource settings
Vaccine Innovation Forum World 2025-中文站点
Melanie Saville
CSO, PATH, USA

Melanie Saville, MBBS, is PATH’s Chief Scientific Officer. She leads PATH’s product development division, which includes a global team dedicated to the development, introduction, and scale of vaccines, medical devices, and diagnostics.

Dr. Saville is a distinguished physician specializing in virology with more than two decades of experience developing and licensing vaccines for global use. Her contributions over the past 20 years have included the development of vaccines for seasonal and pandemic influenza, as well as pediatric combinations and vaccines against rabies, Japanese encephalitis, dengue, Ebola, and SARS-CoV-2.

Before joining PATH, Dr. Saville worked with the Coalition for Epidemic Preparedness Innovations (CEPI), where she served as the Executive Director of Vaccine Research and Development, leading technical teams supporting vaccine development. She also served as the R&D and manufacturing workstream leader for COVAX, part of a global collaboration to speed development, production, and equitable access to COVID-19 tests, treatments, and vaccines.

Dr. Saville holds a medical degree, a master’s degree in medical virology, and a Bachelor of Science in molecular biology from University College, London.


Chair
Vaccine Innovation Forum World 2025-中文站点
Ling Chen
Professor, Guangzhou Laboratory

Dr. Chen has been a Professor at the State Key Lab of Respiratory Disease, Guangzhou Medical University since 2013. Dr. Chen received a medical degree from Shanghai Medical College in 1984. He obtained a Ph.D. in Biochemistry and Molecular Biology from Indiana University School of Medicine. Dr. Chen completed his postdoctoral training at Dana-Farber Cancer Institute, Harvard Medical School.  From 1997-2001, Dr. Chen served as a Senior Research Fellow at Merck Research Laboratories, where he was the first inventor of Merck's Ad5-based AIDS vaccine that entered clinical trials worldwide. Dr. Chen served as Vice President of R&D for GlaxoSmithKline in 2009-2011 and as Vice President at Sanofi Pasteur in 2012. Dr. Chen has over 200 publications in infectious diseases, vaccine research, and cancer research. His current research is focused on vaccine and antibody research on adenovirus, influenza virus, and emerging viruses. Since 2020, Dr. Chen has been working on developing user-friendly intranasal vaccines and mucosal immunity.

Vaccine Innovation Forum World 2025-中文站点
Diana Boraschi
Distinguished Professor, Shenzhen Institute of Advanced Technology, China
Diana Boraschi is an immunologist that built her experience in academic institutions and industrial settings in her home country (Italy) and abroad (USA, France, Austria, Korea, Brazil). She is Senior Associate Researcher at the Italian National Research Council (where she served as Institute Director) and at the Stazione Zoologica Anton Dohrn in Napoli, Italy, and Academician of the Accademia dei Fisiocritici. She is currently serving as Distinguished Professor at the Department of Pharmacology at the Shenzhen Institute of Advanced Technologies (SIAT) of the Chinese Academy of Sciences, in Shenzhen, China. She is author of over 200 peer-reviewed research articles in immunology (h-index 67, over 16000 citations), in addition to many books and book chapters, and inventor in eight patents. In 2017, she has received an honorary PhD degree by the University of Salzburg (Austria), in 2020 the High-Level Talents Program Award for Foreign Scholars, and in 2022 the Chinese Government Friendship Award. She is listed within the first 2% scientists worldwide since 2017 and in the first 1% since 2020. Her area of expertise is innate immunity and inflammation, in particular in relation to autoimmune, inflammatory and degenerative diseases, and vaccine development. Her focus on macrophages and cytokines of the IL-1 superfamily (a bioactive IL-1 domain is known as the “Boraschi loop”), and the interaction of engineered nanomaterials with immunity in humans and environmental species. She is particularly involved in higher education training activities in Europe, Asia, Africa, and South America, with a focus on poverty-related diseases.
Systemic and mucosal immunity: separate roles and cooperation
Vaccine Innovation Forum World 2025-中文站点
Rita Carsetti
国际免疫学会联盟副主席;意大利Bambino Gesù儿童医院教授

Rita Carsetti trained in Medicine and Obstetrics and Gynecology at La Sapienza University of Rome (Italy) before discovering her passion for science during her postdoctoral training in the United States, at the M.D. Anderson Hospital in Houston (Texas). She followed this with a second postdoc at the Max-Plank Institute for Immunobiology in Freiburg (Germany), in the department of Georges Koehler, who had received the Nobel Prize for the discovery of monoclonal antibodies. At the Max-Planck she also became responsible for the flow cytometry core facility and later worked in the departments of Michael Reth and Thomas Boehm. After 13 years in Germany, she returned to Italy (Bambino Gesù Children’s Hospital, Rome) with a strong background in basic immunology of murine B cells. At this point she turned her attention to human B cells for a more patient-orientated research approach. The close contact with clinicians and her role as head of the Diagnostic Immunology Unit gave her the possibility to learn how human B cells change with age, immunodeficiency, infection, transplantation, and vaccination. The COVID-19 pandemic and the global vaccination campaign gave her the possibility to learn more about the development, function, and persistence of human memory B cells after vaccination in healthy subjects and patients with primary or secondary immunodeficiencies. Throughout her career, Rita Carsetti has made a number of discoveries regarding the development of human and murine B cell populations and the effect changes in such populations have on infection and immunodeficiencies in humans. Her recent work on SARS-CoV-2 and RNA vaccination has been vital in demonstrating how human memory B cells aid immune protection and how mucosal immunity is induced in neonates born to SARS-CoV-2 infected mothers. Altogether, Rita Carsetti’s work is extremely relevant to both basic and clinical immunologists.

Inhaled Adenovirus (Human type 5) Vectored Tuberculosis Vaccine
Vaccine Innovation Forum World 2025-中文站点
徐方
高级科学家,康希诺生物,中国

Ph.D. in Molecular Virology from Wageningen University, the Netherlands. Formerly served as a researcher at the Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac) in Canada, the Australian National University, and the University of Amsterdam, focusing on the molecular pathogenesis of influenza virus, respiratory syncytial virus, and baculovirus, as well as vaccine development for respiratory diseases. Currently employed at CanSino Biologics Inc. as a Senior Scientist in the R&D Center. Leading and driving major R&D projects and international collaborations within the company. As a project leader, working on the development of an inhaled adenovirus-vectored tuberculosis vaccine and dedicated to advancing mucosal vaccines and novel vaccine delivery technologies.

The nose knows why and how
Vaccine Innovation Forum World 2025-中文站点
Huimin Yan
Professor, Fudan University
A sequential Intranasal Protein Vaccine Triggers Class Switching from Intramuscularly Primed IgG to Mucosal IgA against SARS-CoV-2
Vaccine Innovation Forum World 2025-中文站点
彭华
研究员,广州实验室,中国

Hua Peng, Ph.D., Principal Investigator at the Guangzhou National laboratory (GNL). Dr. Hua Peng graduated from Peking University, Health Science Center with a bachelor's degree, and completed his doctoral and postdoctoral training in virology at the State University of New York at Buffalo and the National Institutes of Health (LVD/NIAID/NIH). Prior to joining GNL, Dr. Peng held positions as associate Prof./Prof./PI at the Institute of Biophysics, Chinese Academy of Sciences. Her research focuses on 1) Investigating host immune response to virus infection, viral pathogenic mechanism, and virus-associated malignancy; and 2) Developing innovative preventive and therapeutic vaccines against viral infections and immune based anti-cancer drugs. Dr. Hua Peng has made important scientific and translational achievements, publishing in prestigious journals including Gut, Cell Res., Sci Immun., JEM, JCI, Gastro, Nat Commun., PNAS, Nat Med, Nat Immun., Hepatology, Clin Can Res, JI, JBC, and JV. Prof. Peng’s team invented a new-generation SARS-CoV-2 recombinant vaccine, leading to the approval of the vaccine product V-01 and its iterative vaccine BV-01-QX for emergency use in collaboration with Livzon Bio.


茶歇
From Design to lmmunogenicity: An Intranasal Respiratory Syncytial Virus Vaccine Targeting Prefusion F Protein
Vaccine Innovation Forum World 2025-中文站点
魏霞蔚
研究员,四川大学华西医院

魏霞蔚,四川大学华西医院研究员,博导,长江学者特聘教授,国家优秀青年基金获得者。 2010年毕业于浙江大学药物制剂系毕业获得学士学位,于四川大学华西药学院药剂系毕业获得博士学位。现任四川大学华西医院国际合作与交流办公室·港澳台事务办公室主任。任国家老年疾病临床医学中心副主任,华西医院老年与衰老医学研究室主任。任美国基因与细胞治疗协会分委会委员,任亚太地区基因/细胞治疗联盟青年主席。主要研究方向包括:重组蛋白疫苗与佐剂研发、鼻喷疫苗与新型疫苗递送系统、肺部炎性疾病与肿瘤免疫微环境研究、抗肿瘤小分子药物的转化研究等。在 Nature、Nature Communications、EMBO Molecular Medicine、Advanced Science、Molecular Cancer、ACS Nano等发表SCI论文,其中以通讯作者或第一发表SCI论文110篇(H-index=56)。担任4种SCI杂志的编委(Editorial Board Member)或副主编,获得2018年药明康德学者奖。


Swab and Spray: Precision Vaccination with Nasal Vaccines
Vaccine Innovation Forum World 2025-中文站点
Ling Chen
Professor, Guangzhou Laboratory

Dr. Chen has been a Professor at the State Key Lab of Respiratory Disease, Guangzhou Medical University since 2013. Dr. Chen received a medical degree from Shanghai Medical College in 1984. He obtained a Ph.D. in Biochemistry and Molecular Biology from Indiana University School of Medicine. Dr. Chen completed his postdoctoral training at Dana-Farber Cancer Institute, Harvard Medical School.  From 1997-2001, Dr. Chen served as a Senior Research Fellow at Merck Research Laboratories, where he was the first inventor of Merck's Ad5-based AIDS vaccine that entered clinical trials worldwide. Dr. Chen served as Vice President of R&D for GlaxoSmithKline in 2009-2011 and as Vice President at Sanofi Pasteur in 2012. Dr. Chen has over 200 publications in infectious diseases, vaccine research, and cancer research. His current research is focused on vaccine and antibody research on adenovirus, influenza virus, and emerging viruses. Since 2020, Dr. Chen has been working on developing user-friendly intranasal vaccines and mucosal immunity.

Open discussion
Chair
Vaccine Innovation Forum World 2025-中文站点
Jeff Zhu
CEO, Ruizhou Bio

Dr. Jeff Zhu is the founder and CEO of Shanghai Reinovax Biologics co., Ltd., a fast-growing biotech company focusing on discovery and development of innovative vaccines and other biologics. Dr. Zhu has over 20 years’ industrial experience on discovery and development of small molecules, recombinant proteins, antibodies and vaccines from the early discovery to clinical trials. He played an important role in moving multiple drug candidates from the initiation to the clinical trial stage during his 13-year tenure at Pfizer’s R & D center in San Diego. Dr. Zhu moved back to China in 2011, and served as CSO and head of the R & D at Hualan Biological Engineering Inc., and two years later worked as senior director and department head in USP, Shanghai. Dr. Zhu published earned his Ph.D. degree on biological sciences from UC, Irvine, M.S. degree on biochemistry from Georgetown university, and B.S. degree on chemistry from Tsinghua university.

The urgent need for new combination vaccines
Vaccine Innovation Forum World 2025-中文站点
Christopher Gill
Senior Program Officer, Vaccine Clinical Developmenta Gates Foundation, UK

Christopher Gill has an MD from the University of Massachusetts Medical School and an MS from the Tufts School of Graduate Biomedical Studies.  Dr. Gill is an infectious disease specialist by training. From 2002-2008 and again from 2011-2023 he was a faculty member of the Department of Global Health at Boston University School of Public Health rising eventually to the level of full professor of Global Health.  During the intervening years 2008-11 he was the clinical director for the development of the MenACWY-CRM conjugate meningitis vaccine for Novartis Vaccines and Diagnostics. His work has centered broadly on child-survival in the areas of diarrheal diseases, pneumonia, and neonatal survival. However, his largest concentration of work has focused on better understanding the epidemiology of pediatric respiratory infections, notably Streptococcus pneumoniae, Bordetella pertussis and Respiratory Syncytial Virus.  At BU, Dr. Gill was the 2015 recipient of the Norman Scotch Award for excellence in teaching at Boston University School of Public Health, and the 2016 recipient of Boston University's Metcalf Cup and Prize. The Metcalf Cup and Prize is BU's highest teaching honor and is awarded to one of BU's >3500 faculty across its 17 colleges and schools each year.  At the Gates Foundation, Dr. Gill’s main areas are development of combination vaccines and expanding the impact of HPV vaccination globally. 



Rational design and generation of a noval recombinant Pseduomonas areaginosal subunit vaccine
Vaccine Innovation Forum World 2025-中文站点
顾江
教授,副主任,陆军军医大学

顾江,陆军军医大学国家免疫生物制品工程技术研究中心副主任、教授,博士生导师,国家重点研发计划首席科学家,“国防优才基金”获得者,军队高层次青年英才,陆军科技英才,陆军军医大学科研名师,享受军队优秀专业技术人才津贴。国家重点领域严重感染致病菌疫苗研发创新团队核心骨干;重庆英才创新创业示范团队核心骨干。中国疫苗行业协会细菌感染与疫苗研究专委会常委、秘书长,重庆微生物学会理事。先后获重庆市技术发明一等奖、军队科技进步二等奖等奖励。主要从事结构疫苗学基础与临床研究,围绕超级耐药菌的免疫干预展开,研制了1.1类新药——基因工程铜绿假单胞菌疫苗实现成果转化,合同金额2.8亿元。


Prophylactic Product Development and Manufacturing for Global Health Partners - A Systematic Approach
Vaccine Innovation Forum World 2025-中文站点
Zhihui Qiu
Head of Alliance Management, WuXi Vaccines, China

Dr. Qiu has 20 years of experience in pharmaceutical development and alliance management.

Joining WuXi Vaccines in 2021, she is the Head of Alliance Management in charge of collaborating with global partners, establishing and expanding relationship with international organizations, and driving the global health initiatives.

Before joining WuXi Vaccines, she was the project leader in Schering Plough Research Institute and Novartis Pharmaceutical Corp. in US. In 2014, she joined WuXi AppTec as Director of Alliance Management and Program Management, managing key collaborations with MNCs and developed program strategy for its first ADC project. Later she established the proposal team in WuXi Biologics, which facilitated its rapid expansion in late stage and commercial business development. 


Harnessing mRNA Technology to Combat Antimicrobial Resistance: Pioneering Vaccines for Drug-Resistant Bacteria
Vaccine Innovation Forum World 2025-中文站点
费才溢
澄实生物创始人、副总裁

Graduated with a Ph.D. in Bioinformatics from the University of Science and Technology of China in 2014, under the guidance of Professor Liu Haiyan. Many years of experiences in molecular dynamics simulation and high-throughput sequencing, and have served as the Director of Bioinformatics for Micro Spin Genes and the Head of Nucleic Acid Drug Development for Yidu Cloud. Successfully developed multiple clinical high-throughput data analysis platforms and have authored multiple invention patent authorizations and SCI papers. As the co-founder of Therarna, responsible for identifying and optimizing upstream targets of mRNA drugs, leading the team to develop a systematic platform for identifying cross species cellular immune epitopes, designing humoral immune antigens, and optimizing mRNA sequences.

茶歇
Isolation of protective monoclonal antibodies and development of novel fusion protein vaccines against tuberculosis
Vaccine Innovation Forum World 2025-中文站点
李浩
中国农业大学动物医学院副教授

李浩,中国农业大学动物医学院副教授,博士生导师。2017年7月在清华大学获得理学博士学位。2017年7月到2019年7月在清华大学医学院从事博士后研究工作。2019年7月至今,在中国农业大学动物医学院从事结核病免疫学和抗生素耐药性相关研究。主持国自然面上和中国博士后基金各1项,国家重点研发计划研究任务1项,参与国自然3项。以第一或通讯作者(含共同)在Nature Reviews Immunology,PNAS,Nature Communications,npj Vaccines等杂志发表相关文章30余篇。


More than a theory - Successful vaccination by Micro Array Patches
Vaccine Innovation Forum World 2025-中文站点
Markus Winterberg
Head, Analytical Development, Microbiology, Quality Control – MAP Program, LTS, Germany

Markus is Head of Analytical Development, Microbiology, and Quality Control for the MAP-Program at LTS Lohmann Therapie Systeme AG in Andernach. He studied biology at Philipps University in Marburg, Germany, and was awarded a PhD in Parasitology in 2009 for his work on the membrane physiology and biochemistry of the Malaria parasite. From 2009 to 2015 he expanded his track record in infectious disease research at The Australian National University in Canberra, Australia. In 2015, he accepted a position for the University of Oxford, leading the Clinical Pharmacology laboratories at the Mahidol-Oxford Tropical Medicine Research Unit in Bangkok, Thailand. In 2019 he joined LTS as Head of Analytical Development, Microbiology and Quality Control for the MAP Program.


A High-Density Microarray Patch (HD-MAP) to Improve Effectiveness of Vaccines
Vaccine Innovation Forum World 2025-中文站点
Thomas Lake
SVP Vaccine Alliances, Vaxxas, Autralia

Mr. Lake has worked in vaccine manufacturing and commercialization for 30 years developing diverse experience at global leaders Merck and GlaxoSmithKline. Mr. Lake's background includes live virus and recombinant vaccine bulk production, sterile filling, and quality control, before moving into product management and business development roles. He served as the manufacturing Alliance Manager between Merck and Sanofi Pasteur during the startup of their European loint Venture and worked for several years as asenior level commercialization consultant in the vaccine industry.

午餐
Chair
Vaccine Innovation Forum World 2025-中文站点
成百麟
韩国疫苗创新技术联盟总干事

Baik-Lin Seong, PhD, is a Distinguished Professor of Yonsei University College of Medicine, and Director General of Vaccine Innovative Technology ALliance (VITAL)-Korea. He received B.S. from Seoul National University (1977), M.S. from KAIST (1979), PhD from MIT (1988). He worked as postdoctoral scientist at the University of Oxford (1988-1992).

He served as a member of the Presidential Advisory Council of Science & Technology of Korean Government (2021-2022) and the Scientific Advisory Board of International Vaccine Institute (IVI) (2018-2022). He chaired the COVID-19 Vaccine Pan-Government Strategic Plan of the Korean Government (2020-2023).

With a view to ensure equitable access of effective vaccines to LMICs, he works on developing a low-cost production platform of VLP/nanoparticle vaccines against RSV, norovirus, nipah, universal influenza vaccine, and flavivirus vaccines including Japanese Encephalitis, Zika, and West Nile viruses.


Malaria Vaccines: from Licensure to Elimination
Vaccine Innovation Forum World 2025-中文站点
Adrian V. S. Hill
Director, The Jenner Institute, Professor, University of Oxford , UK

Professor Adrian V. S. Hill FRS is the Director and Founder of the Jenner Institute, and Mital Professor of Vaccinology at Oxford University. He is a passionate believer in the power of molecular medicine to address many of the most egregious health care inequities globally. His group have been leaders in the development of adenoviral and other vaccines against infectious diseases and he has tested these in extensively in over eighty clinical trials in Africa and Europe. In partnership with the Serum Institute of India and AstraZeneca the Jenner Institute developed rapidly a ChAdOx1 vector-based SARS-CoV-2 vaccine which saved an estimated 6.2 million lives in 2021 alone.

His lab also designed a newly licensed high efficacy malaria vaccine, R21/Matrix-MTM, which has recently shown unprecedented high efficacy in a phase III trial in four African countries, again in partnership with the Serum Institute of India and also Novavax Inc. This vaccine promises to make a major impact on reducing the 500,000 childhood deaths from malaria each year. In 2021 he was elected a Fellow of the Royal Society and is a Knight Commander of the Order of the British Empire (KBE).


Rational design of Zika vaccine to eliminate dengue enhancement
Vaccine Innovation Forum World 2025-中文站点
戴连攀
中科院微生物研究所研究员

Lianpan Dai, PhD, Principal Investigator at Institute of Microbiology, Chinese Academy of Sciences. He received his doctor's degree from Technical University of Munich (TUM), Germany. His research is mainly focused on the design and development of novel vaccines against major pathogens and the mechanism of protective immune response. Important research and translational achievements have been made in the research and development of vaccines against coronaviruses, Zika virus and other emerging infectious diseases, among which the recombinant protein subunit COVID-19 vaccine has been approved for use in many countries. The results are published as first/corresponding authors in the journals including Cell, The New England Journal of Medicine, Lancet, Nature Immunology, Nature Reviews Immunology, Cell Host & Microbe. He is supported by the National Science Fund for Excellent Young Scholars, and is the winner of VCANBIO Award for Biosciences and Medicine, excellent member of the Innovation Promotion Association of Chinese Academy of Sciences, the Young Scholar Award of Chinese Society of Immunology, and China Patent Silver Award Winner.


Innovative immunogen design for mpox virus vaccine development
Vaccine Innovation Forum World 2025-中文站点
王寒
北京大学副教授

王寒,北京大学未来技术学院副研究员,疫苗研究团队负责人。主要从事病毒感染机制和抗病毒干预策略研究,在包括埃博拉病毒、猴痘病毒和非洲猪瘟病毒在内的多种重要病毒性传染病原的入侵和复制机制、疫苗、抗病毒药物研究中取得了一系列重要进展。以第一和通讯作者(含共同)在Cell、Nature Immunology、PNAS、Nucleic Acids Research等国际期刊上发表论文多篇,获“2016年度中国生命科学领域十大进展”。入选博士后创新人才支持计划、北京市科协“青年人才托举工程”、中国科学院青年创新促进会;任 hLife 期刊青年编委,北京慢性病防治与健康教育研究会感染性疾病专业委员会委员。

Harnessing Opportunities: Unlocking the Potential for Clinical Trials in Africa
Vaccine Innovation Forum World 2025-中文站点
Christopher Obwanga